Results 11 to 20 of about 59,989 (270)

Sleep disruption due to nocturnal heartburn: a review of the evidence and clinical implications

Exploration of Medicine, 2023
Nocturnal heartburn (NHB) is a symptom that affects up to 25% of the general population and has been shown to cause sleep disruption that adversely affects quality of life and psychomotor performance.
David A. Johnson, Amisha M. Parikh-Das, Evren Atillasoy, Hayk Davtyan, Leslie Shur, Andrea S. Blevins-Primeau, Nathaniel F. Watson   +6 more
doaj   +1 more source

Multicenter study of gastroesophageal reflux disease symptoms prevalence in outpatients in Russia

Терапевтический архив, 2022
Background. Recently, there has been an increase in the prevalence of gastroesophageal reflux disease (GERD) in Northern Europe, North America and East Asia. However data on GERD prevalence in Russian population are very limited. Aim. To determine the
Dmitry S. Bordin, Rustam А. Abdulkhakov, Marina F. Osipenko, Alla V. Solovyeva, Sayar R. Abdulkhakov, Nikolay P. Kirilenko, Mikhail A. Butov, Olga I. Berezina, Elen R. Valitova, Dilyara D. Safina, Ilmira M. Alieva, Maria A. Livzan, Aiman S. Sarsenbaeva, Galina N. Tarasova, Yulia V. Embutnieks, Indira R. Mubarakshina, Ilshat Kh. Khayrullin, Alla G. Kononova, Sergey V. Kolbasnikov, Igor V. Maev   +19 more
doaj   +1 more source

Phenotypes of gastroesophageal reflux disease: classification, pathogenesis and diagnostic criteria: A review

Consilium Medicum, 2022
The literature review focuses on the current understanding of visceral hypersensitivity mechanisms in the esophagus. Mechanisms of peripheral and central sensitization and their relation to heartburn symptoms are covered in detail.
Igor V. Maev, Elena V. Barkalova, Mariia A. Ovsepian, Dmitry N. Andreev   +3 more
doaj   +1 more source

Heartburn Sensation in Non-Erosive Reflux Disease: Pattern of Superficial Sensory Nerves Expressing TRPV1 and Epithelial Cells Expressing ASIC3 Receptors.

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2021
The underlying causes of heartburn, characteristic symptom of gastro-esophageal reflux disease(GERD), remain incompletely understood. Superficial afferent innervation of the esophageal mucosa in nonerosive reflux disease(NERD) may drive nociceptive ...
A. Ustaoglu, Akinari Sawada, Chung Lee, W. Lei, Chien‐Lin Chen, R. Hackett, D. Sifrim, M. Peiris, P. Woodland   +8 more
semanticscholar   +1 more source

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source

The importance of functional diagnostics in determining the cause of antisecretary therapy inefficiency in a patient with heartburn: clinical observation

Медицинский совет, 2021
One of the main symptoms of gastroesophageal reflux disease is heartburn, for the relief of which proton pump inhibitors are traditionally prescribed. However, there are frequent cases of heartburn, refractory to antisecretory therapy, when there is no ...
E. V. Barkalova, D. N. Andreev, M. A. Ovsepian   +2 more
doaj   +1 more source

Heartburn in children and adolescents in the presence of functional dyspepsia and/or irritable bowel syndrome correlates with the presence of sleep disturbances, anxiety, and depression

Medicine, 2021
The aim of this study was to assess the relationship of heartburn in pediatric patients with functional dyspepsia (FD) and irritable bowel syndrome (IBS) with gastrointestinal symptoms, sleep disturbances, and psychologic distress.
J. Colombo, Amanda D. Deacy, J. Schurman, C. Friesen   +3 more
semanticscholar   +1 more source

The Prevalence and Risk Factors of GERD Among Indonesian Medical Doctors [PDF]

, 2016
Background: Based on our knowledge, the study of gastrointestinal reflux disease (GERD) among certain profession has never been conducted. The aim of this study is to determine the prevalence and risk factors of GERD among Indonesian doctors.
Hapsari, P. F. (Puspita), Makmun, D. (Dadang), Syam, A. F. (Ari)   +2 more
core   +3 more sources

The role of antacids in diseases related to excessive secretion of hydrochloric acid

Farmacja Polska, 2021
Antacids are known from the earliest times. This is a group of compounds of various chemical structures and a common mechanism of action consisting in the neutralization of hydrochloric acid and raising gastric pH.
Marcin Janiaczyk, Magdalena Ogrodowczyk
doaj   +1 more source

IW-3718 Reduces Heartburn Severity in Patients With Refractory Gastroesophageal Reflux Disease in a Randomized Trial.

Gastroenterology, 2020
BACKGROUND AIMS Refractory gastroesophageal reflux disease (GERD) reduces quality of life and creates significant financial burden on the healthcare system.
M. Vaezi, R. Fass, N. Vakil, D. Reasner, R. Mittleman, Michael J. Hall, J. Z. Shao, Yan Chen, Lara Lane, Amy M. Gates, M. Currie   +10 more
semanticscholar   +1 more source