Results 271 to 280 of about 337,577 (311)

Heat Shock Protein 70

1999
One of the most interesting aspects of thermal biology in the mammalian system is the response of heated cells to subsequent heat challenges. When exposed to a mild, non-lethal heat shock, mammalian cells develop a transient resistance to subsequent thermal stress (thermotolerance).
G. C. Li, N. F. Mivechi
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Heat Shock Protein 70 Expression Kinetics

Advances in Heat and Mass Transfer in Biotechnology, 2002
HSP70 is well known for its major role in cardiac ischemia protection. The purpose of this study was to determine the HSP70 expression kinetics for new protocol design in cardiac surgery, based on HSP70 protection function in clinical applications. Bovine aortic endothelial cells (BAEC) were used in experiments.
Sihong Wang, Kenneth R. Diller, Shanti J. Aggarwal   +2 more
openaire   +1 more source

Therapeutic Use of Heat Shock Protein 70

Recent Patents on DNA & Gene Sequences, 2007
All living organisms use protein to perform essential functions. However, environmental factors induce stress and relevant proteins that may not function properly. Inappropriate misfolding and aggregation are major issues in functioning of a protein and this may impact critical cellular processes implicated in diseases.
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cDNA of Canine Heat Shock Protein 70 (HSP70)

Veterinary Research Communications, 2004
Full-length canine HSP70 cDNA was sequenced and the expression of HSP70 mRNA was investigated. The full-length cDNA sequence of the HSP70 gene (2322 bp) contained a single long open reading frame (1920 bp) coding a protein of 640 amino acids. The amino acid sequence of the canine HSP70 gene shared about 90-95% sequence similarity with bovine, human and
R, Kano, K, Abe, A, Hasegawa
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Heat-shock protein 70 antagonizes apoptosis-inducing factor

Nature Cell Biology, 2001
Heat-shock protein 70 (Hsp70) has been reported to block apoptosis by binding apoptosis protease activating factor-1 (Apaf-1), thereby preventing constitution of the apoptosome, the Apaf-1/cytochrome c/caspase-9 activation complex [1,2]. Here we show that overexpression of Hsp70 protects Apaf-1-/- cells against death induced by serum withdrawal ...
Ravagnan, Luigi, Gurbuxani, Sandeep, Susin, Santos A., Maisse-Paradisi, Carine, Daugas, Eric, Zamzami, Naoufal, Mak, Tak, Jäättelä, Marja, Penninger, Josef M., Garrido, Carmen, Kroemer, Guido   +10 more
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Heat Shock Protein 70 and Cancer

2018
Heat shock proteins (HSP) constitute a large family of proteins involved in protein folding and maturation and the expressions of HSP are induced by heat shock or other stressors. The major groups, which are classified based on their molecular weight, include HSP27, HSP40, HSP60, HSP70, HSP90, and large HSP (HSP110 and glucose-regulated protein 170 ...
Tuoen Liu, Shousong Cao
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Heat-shock protein 70: molecular supertool?

Pediatric Nephrology, 2005
The cellular stress response decreases cellular injury, either via primary induction of cytoresistance or by secondary enhancement of cellular repair mechanisms. The most frequently studied and best understood effectors of the cellular stress response are the heat shock proteins (HSP).
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Heat Shock Protein 70 and Other Heat Shock Proteins in Diseased Retina

2018
Heat shock proteins (HSP) belong to a family of stress-induced proteins essential to cell survival. HSP have multiple protective roles through assistance in protein folding, maintaining mitochondrial homeostasis, suppressing proinflammatory cytokines, resisting ischemic damage and protecting cells from apoptotic and necrotic death.
Ting Zhang, Bobak Bahrami, Ling Zhu
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Heat shock protein 70 and antibodies to heat shock protein 60 are associated with cerebrovascular atherosclerosis

Clinical Biochemistry, 2016
Heat shock proteins (Hsps) are produced by all cells, including vascular, to ensure stress protection. Damaged cells release Hsps in their local environment and systemic circulation. The aim of this study was to investigate the involvement and prognostic utility of serum Hsp60 and Hsp70, and the respective antibodies anti-Hsp60 and anti-Hsp70 in ...
Galović, Ružica, Flegar-Meštrić, Zlata, Vidjak, Vinko, Matokanović, Mirela, Barišić, Karmela   +4 more
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Kinetics Study of Endogenous Heat Shock Protein 70 Expression

Journal of Biomechanical Engineering, 2003
The purpose of this study was to determine the kinetics of HSP70 expression in response to mild thermal stress. The rationale is to produce a basis for design of optimal heating methods to induce HSP70 expression for preconditioning in cardiac surgery. Bovine aortic endothelial cells were heated at 42°C for 0.5 to 5 hours followed by 37°C recovery for ...
Sihong, Wang, Kenneth R, Diller, Shanti J, Aggarwal   +2 more
openaire   +2 more sources