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Functional interplay between heat shock protein 90 (HSP90) and heat shock factors (HSFs) [PDF]

open access: yesCell Stress & Chaperones
Maintenance of protein homeostasis, also known as proteostasis, is essential for cellular survival under both basal and stress conditions. Proteostasis relies on a coordinated action between molecular chaperones, such as heat shock proteins (HSPs), and ...
Abir Chakraborty   +2 more
doaj   +2 more sources

The development of cancers research based on mitochondrial heat shock protein 90 [PDF]

open access: yesFrontiers in Oncology, 2023
Mitochondrial heat shock protein 90 (mtHsp90), including Tumor necrosis factor receptor-associated protein 1 (TRAP1) and Hsp90 translocated from cytoplasm, modulating cellular metabolism and signaling pathways by altering the conformation, activity, and ...
Yuchu Xiang   +9 more
doaj   +2 more sources

Heat shock protein 90 is a chaperone regulator of HIV-1 latency. [PDF]

open access: yesPLoS Pathogens
An estimated 32 million people live with HIV-1 globally. Combined antiretroviral therapy suppresses viral replication but therapy interruption results in viral rebound from a latent reservoir mainly found in memory CD4+ T cells.
Somaya Noorsaeed   +3 more
doaj   +2 more sources

Heat shock protein 90: biological functions, diseases, and therapeutic targets [PDF]

open access: yesMedComm
Heat shock protein 90 (Hsp90) is a predominant member among Heat shock proteins (HSPs), playing a central role in cellular protection and maintenance by aiding in the folding, stabilization, and modification of diverse protein substrates. It collaborates
Huiyun Wei   +7 more
doaj   +2 more sources

Correction: Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma. [PDF]

open access: yesPLoS ONE
[This corrects the article DOI: 10.1371/journal.pone.0056134.].
Xinqi Wu   +2 more
doaj   +2 more sources

Heat shock proteins: a therapeutic target worth to consider [PDF]

open access: yesVeterinary World, 2015
Heat shock proteins (HSPs) are the molecular chaperones, that are not only expressed during the normal growth process of cell cycle consecutively, but also get induced in cells during various stress conditions produced by cellular insult, environmental ...
Amita Dubey   +3 more
doaj   +1 more source

Heat shock protein 90 has roles in intracellular calcium homeostasis, protein tyrosine phosphorylation regulation, and progesterone-responsive sperm function in human sperm. [PDF]

open access: yesPLoS ONE, 2014
Heat shock protein 90 plays critical roles in client protein maturation, signal transduction, protein folding and degradation, and morphological evolution; however, its function in human sperm is not fully understood.
Kun Li   +7 more
doaj   +1 more source

Evaluation of Plasma Heat Shock Protein Levels in Smokers

open access: yesAddicta: The Turkish Journal on Addictions, 2022
This study aims to evaluate the effects of smoking on extracellular heat shock protein levels. Heat shock proteins have been associated with numerous diseases.
Muhammet Kızmaz   +3 more
doaj   +1 more source

Differential expression of heat shock protein 90, 70, 60 in chicken muscles postmortem and its relationship with meat quality [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2017
Objective The aim of this study was to investigate the expression of heat shock protein (HSP) 90, 70, and 60 in chicken muscles and their possible relationship with quality traits of meat. Methods The breast muscles from one hundred broiler chickens were
Muhan Zhang   +7 more
doaj   +1 more source

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