Heat shock protein 90 inhibition in the endothelium [PDF]
Frontiers in Medicine, 2023 Nektarios Barabutis
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Potential role of heat shock protein 90 (Hsp90) in HIV uncoating [PDF]
Retrovirology, 2011 Stoddart Cheryl A, Joshi Pheroze
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Activity of the heat shock protein 90 inhibitor ganetespib in melanoma. [PDF]
PLoS ONE, 2013 Heat shock protein 90 (HSP90) is involved in the regulation of diverse biological processes such as cell signaling, proliferation and survival, and has been recently recognized as a potential target for cancer therapy.
Xinqi Wu +2 more
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The development of cancers research based on mitochondrial heat shock protein 90 [PDF]
Frontiers in Oncology, 2023 Mitochondrial heat shock protein 90 (mtHsp90), including Tumor necrosis factor receptor-associated protein 1 (TRAP1) and Hsp90 translocated from cytoplasm, modulating cellular metabolism and signaling pathways by altering the conformation, activity, and ...
Yuchu Xiang +9 more
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Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics [PDF]
Open Biology, 2012 Heat shock protein 90 (Hsp90) is a promising cancer drug target as a molecular chaperone critical for stabilization and activation of several of the oncoproteins that drive cancer progression.
Peter W. Piper, Stefan H. Millson
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Heat shock protein 90 is a chaperone regulator of HIV-1 latency. [PDF]
PLoS PathogensAn estimated 32 million people live with HIV-1 globally. Combined antiretroviral therapy suppresses viral replication but therapy interruption results in viral rebound from a latent reservoir mainly found in memory CD4+ T cells.
Somaya Noorsaeed +3 more
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Heat shock protein 90: biological functions, diseases, and therapeutic targets [PDF]
MedCommHeat shock protein 90 (Hsp90) is a predominant member among Heat shock proteins (HSPs), playing a central role in cellular protection and maintenance by aiding in the folding, stabilization, and modification of diverse protein substrates. It collaborates
Huiyun Wei +7 more
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Editor's Note on: Structural Basis for Depletion of Heat Shock Protein 90 Client Proteins by Deguelin. [PDF]
J Natl Cancer Inst, 2023 Seung Oh +4 more
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Correction: Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma. [PDF]
PLoS ONE[This corrects the article DOI: 10.1371/journal.pone.0056134.].
Xinqi Wu +2 more
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Heat shock protein 90 has roles in intracellular calcium homeostasis, protein tyrosine phosphorylation regulation, and progesterone-responsive sperm function in human sperm. [PDF]
PLoS ONE, 2014 Heat shock protein 90 plays critical roles in client protein maturation, signal transduction, protein folding and degradation, and morphological evolution; however, its function in human sperm is not fully understood.
Kun Li +7 more
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