Evaluation of antioxidant property of heat shock protein 90 from duck muscle [PDF]
Animal Bioscience, 2021 Objective The objectives of this study were to investigate the direct antioxidative effect of 90 Kda heat shock protein (Hsp90) obtained from duck muscle.
Muhan Zhang +3 more
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Purification of Mg2+-dependent phosphatidate phosphohydrolase from rat liver: new steps and aspects [PDF]
, 2005 A new procedure for the partial purification of Mg2+-dependent, N-ethylmaleimide-sensitive phosphatidate phosphohydrolase (Mg2+-PAP; EC 3.1.3.4) from rat liver cytosol is described, using protein precipitation with MgCl2, gel filtration on Sephacryl S ...
Hofstetter, Monika M., Siess, Elmar A.
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Pharmaceutical Biology, 2022 Context Vascular calcification is a major complication of chronic renal failure, which has been identified as an active process partly driven by osteogenic transition of vascular smooth muscle cells (VSMCs).
Quanquan Shen +7 more
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Heat Shock Protein 90 (Hsp90) Expression and Breast Cancer
Pharmaceuticals, 2012 Hsp90 is an abundant protein in mammalian cells. It forms several discrete complexes, each containing distinct groups of co-chaperones that assist protein folding and refolding during stress, protein transport and degradation. It interacts with a variety
Christos A. Papadimitriou +3 more
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Discovery of Disubstituted Carboranes as Inhibitors of Heat Shock Protein 90-Heat Shock Factor 1 Interaction. [PDF]
ACS Med Chem LettEfficient synthesis of disubstituted para- and ortho-carboranes (2 and 3, respectively) was achieved. Among the compounds synthesized, 3e showed potent suppression of hypoxia-inducible factor 1 (HIF-1) transcriptional activity under hypoxia by a cell ...
Shao Y +5 more
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Hsp-90 and the biology of nematodes [PDF]
, 2009 BACKGROUND: Hsp-90 from the free-living nematode Caenorhabditis elegans is unique in that it fails to bind to the specific Hsp-90 inhibitor, geldanamycin (GA).
Emes, R.D. +4 more
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Activity of the heat shock protein 90 inhibitor ganetespib in melanoma. [PDF]
PLoS ONE, 2013 Heat shock protein 90 (HSP90) is involved in the regulation of diverse biological processes such as cell signaling, proliferation and survival, and has been recently recognized as a potential target for cancer therapy.
Xinqi Wu +2 more
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Extracellular Heat Shock Protein-90 (eHsp90): Everything You Need to Know
Biomolecules, 2022 “Extracellular” Heat Shock Protein-90 (Hsp90) was initially reported in the 1970s but was not formally recognized until 2008 at the 4th International Conference on The Hsp90 Chaperone Machine (Monastery Seeon, Germany).
Daniel Jay, Yongzhang Luo, Wei Li
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Comparison of heat-shock responses between the hydrothermal vent shrimp Rimicaris exoculata and the related coastal shrimp Palaemonetes varians [PDF]
, 2010 The deep-sea vent shrimp Rimicaris exoculata is believed to occur at the hot end of the hydrothermal biotope in order to provide essential elements to its epibiosis. Because it is found close to hot venting water, R.
Thomas Chertemps +11 more
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Heat Shock Protein 90 Inhibitors repurposed against Entamoeba histolytica
Frontiers in Microbiology, 2015 Hsp90 is an essential chaperone responsible for trafficking a vast array of client proteins, which are substrates that Hsp90 regulates in eukaryotic cells under stress conditions.
Dea eShahinas +4 more
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