Heat shock protein 90: a capacitor or a mutator? [PDF]
Journal of Biosciences, 2010 ISSN:0250 ...
Sawarkar, Ritwick, Paro, Renato
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Hypoglycemia Impairs the Heat Shock Protein Response: A Risk for Heat Shock in Cattle?
Frontiers in Veterinary Science, 2022 BackgroundHeat stress (HS) in cattle is a major debilitating problem, affecting health and milk yield. Physiologically, HS has been shown to lower blood glucose levels to 2.5 mmol/l (45 mg/dl) and results in upregulation of heat shock proteins (HSPs ...
Samuel A. Atkin +3 more
doaj +1 more source
Crowding Activates Heat Shock Protein 90 [PDF]
Journal of Biological Chemistry, 2016 Hsp90 is a dimeric ATP-dependent chaperone involved in the folding, maturation, and activation of diverse target proteins. Extensive in vitro structural analysis has led to a working model of Hsp90's ATP-driven conformational cycle. An implicit assumption is that dilute experimental conditions do not significantly perturb Hsp90 structure and function ...
Jackson C, Halpin +3 more
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Heat shock protein 90 inhibitor RGRN-305 potently attenuates skin inflammation
Frontiers in Immunology, 2023 IntroductionChronic inflammatory skin diseases may have a profound negative impact on the quality of life. Current treatment options may be inadequate, offering an unsatisfactory response or side effects.
Hakim Ben Abdallah +6 more
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Heat Shock Protein 70 and 90 Family in Prostate Cancer
Life, 2022 Prostate cancer (PCa) is the second most frequent cancer that affects aging men worldwide. However, its exact pathogenesis has not been fully elucidated. The heat shock protein (HSP) family has cell-protective properties that may promote tumor growth and
Xun Fu +4 more
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Could Upregulated Hsp70 Protein Compensate for the Hsp90-Silence-Induced Cell Death in Glioma Cells? [PDF]
, 2014 The molecular chaperone heat shock protein 90 alpha (Hsp90α) has been recognized in various tumours including glioma. This pilot study using a proteomic approach analyses the downstream effects of Hsp90 inhibition using 17-allylamino-17 ...
Khan, Zarine Jamsher +3 more
core +4 more sources
Purification of Mg2+-dependent phosphatidate phosphohydrolase from rat liver: new steps and aspects [PDF]
, 2005 A new procedure for the partial purification of Mg2+-dependent, N-ethylmaleimide-sensitive phosphatidate phosphohydrolase (Mg2+-PAP; EC 3.1.3.4) from rat liver cytosol is described, using protein precipitation with MgCl2, gel filtration on Sephacryl S ...
Butterwith +10 more
core +1 more source
Conformational dynamics of a single protein monitored for 24 hours at video rate [PDF]
, 2018 We use plasmon rulers to follow the conformational dynamics of a single protein for up to 24 h at a video rate. The plasmon ruler consists of two gold nanospheres connected by a single protein linker.
Ahijado-Guzmán, Rubén +10 more
core +3 more sources
Vectors for N- or C-terminal positioning of the yeast Gal4p DNA binding or activator domains [PDF]
, 2003 EMTREE drug terms: fungal protein; heat shock protein 90; hybrid protein; transcription factor EMTREE medical terms: amino terminal sequence; article; carboxy terminal sequence; DNA binding; DNA binding domain; expression vector; Gal4p domain; gene ...
Millson, S. H. +2 more
core +1 more source
Evaluation of antioxidant property of heat shock protein 90 from duck muscle [PDF]
Animal Bioscience, 2021 Objective The objectives of this study were to investigate the direct antioxidative effect of 90 Kda heat shock protein (Hsp90) obtained from duck muscle.
Muhan Zhang +3 more
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