Results 61 to 70 of about 309,378 (343)

Bacterial Infection Elicits Heat Shock Protein 72 Release from Pleural Mesothelial Cells [PDF]

, 2013
Heat shock protein 70 (HSP70) has been implicated in infection-related processes and has been found in body fluids during infection. This study aimed to determine whether pleural mesothelial cells release HSP70 in response to bacterial infection in vitro
Bielsa, S, Brown, JS, Creaney, J, della Vergiliana, JFV, Lansley, SM, Lee, YCG, Porcel, JM, Temple, SEL, Waterer, GW   +8 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Recognition of tumor-targeting peptide P7 related to the expression level of Hsp90 [PDF]

Jichu yixue yu linchuang, 2021
Objective To analyze the correlation between the expression of heat shock protein 90 (Hsp90) and the recognition of LPLTPLP (P7) on different tumor tissues and para-carcinoma tissues. Methods The expression of HSP90 and recognition effects of FITC-P7
KONG De-xin, HUANG Wei, YANG Nan, LIU Yan-yong
doaj  

Bronchial thermoplasty in asthma: an exploratory histopathological evaluation in distinct asthma endotypes/phenotypes

Respiratory Research, 2021
Background Bronchial thermoplasty regulates structural abnormalities involved in airway narrowing in asthma. In the present study we aimed to investigate the effect of bronchial thermoplasty on histopathological bronchial structures in distinct asthma ...
Eleni Papakonstantinou, Triantafyllia Koletsa, Liang Zhou, Lei Fang, Michael Roth, Meropi Karakioulaki, Spasenija Savic, Leticia Grize, Michael Tamm, Daiana Stolz   +9 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

Assessing the utility of Hsp90 gene for inferring evolutionary relationships within the ciliate subclass Hypotricha (Protista, Ciliophora)

BMC Evolutionary Biology, 2020
Background Although phylogenomic analyses are increasingly used to reveal evolutionary relationships among ciliates, relatively few nuclear protein-coding gene markers have been tested for their suitability as candidates for inferring phylogenies within ...
Qi Zhang, Jiahui Xu, Alan Warren, Ran Yang, Zhuo Shen, Zhenzhen Yi   +5 more
doaj   +1 more source

Wrapping the alpha-crystallin domain fold in a chaperone assembly [PDF]

, 2005
Small heat shock proteins (sHsps) are oligomers that perform a protective function by binding denatured proteins. Although ubiquitous, they are of variable sequence except for a C-terminal similar to 90-residue "alpha-crystallin domain".
Basha, Basha, Benitez, Benndorf, Bova, Brunger, Bullard, Cashikar, Chen, Christine Slingsby, De Jong, De La Fortelle, Ding, Doublié, Eddy, Ehrnsperger, Evans, French, Fu, Giese, Guido Kappé, Haslbeck, Haslbeck, Head, Heger, Horwitz, Hsu, Irobi, Kappe, Kappé, Kim, Kim, Laskowski, Lee, Leslie, Lindner, MacRae, Mao, McManus, McRee, Merckelbach, Mogk, Mounier, Nene, Orengo, Perng, Rekas, Robin Stamler, Schneider, Sobott, Stromer, Studer, Theriault, Valdez, Van Montfort, van Montfort, Wilbert Boelens, Zourlidou   +57 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

Advanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee, Stefanie S. M. Meier, Sara Trujillo, Andreas Möglich, Shrikrishnan Sankaran   +4 more
wiley   +1 more source