Results 111 to 120 of about 6,062,734 (352)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Mathematical and physical modeling of heat transfer through window with heat-reflecting screens to determine the potential of reducing thermal costs for microclimate parameters maintaining

MATEC Web of Conferences, 2017
A mathematical model describing the process of heat transfer through windows with heat-reflecting screens, taking into account physical and geometrical parameters of the building construction, was developed.
Smirnov Nikolay, Tyutikov Vladimir, Zakharov Vadim   +2 more
doaj   +1 more source

Protocol: Women, work and heat: a systematic review and meta-analysis of occupational heat exposure of women [PDF]

, 2023
Ana Bonell, Leonidas G. Ioannou, Andreas D. Flouris   +2 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Ignition Delay and Reaction Time Measurements of Hydrogen–Air Mixtures at High Temperatures

Fire
Induction and reaction times of hydrogen–air mixtures (ϕ = 0.5–2) have been measured behind reflected shock waves at temperatures of 1000–1600 K, pressures of 0.1, 0.3, 0.6 MPa in the domain of the extended second explosion limit.
Yauhen Baranyshyn, Vyacheslav Kuzmitski, Oleg Penyazkov, Kirill Sevrouk   +3 more
doaj   +1 more source

Experimental investigation of a forced convection heat transfer of the organic fluid R-125 at supercritical pressures and under organic rankine cycle conditions [PDF]

, 2017
The organic Rankine cycle (ORC) is a suitable technology for utilizing low-grade temperature heat sources of ~100 °C from various industry processes. In the ORC cycle an organic fluid with a lower boiling point is used as a working medium.
Billiet, Marijn, De Paepe, Michel, Kaya, Alihan, Lazova, Marija, Lecompte, Steven   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

[Heat illness].

Nederlands tijdschrift voor geneeskunde, 2023
Thermoregulation keeps the normal body temperature of humans at approximately 37 °C. However, as a result of heat load - both endogenous and exogenous heat - it can occur that the body is unable to dissipate excess heat, leading to an increase in the core body temperature.
Hoek, Amber E., Dollee, Nathalie, Prins, Gerrie, Alsma, Jelmer   +3 more
openaire   +2 more sources

PERFORMANCE PREDICTION OF CENTRIFUGAL PUMPS WITH CFD-TOOLS

TASK Quarterly, 2001
The CFD-code FLUENT, version 5.4, has been used for the flow analysis of two test pumps of end-suction volute type: one of low specific speed and one of medium specific speed.
ERIK DICK, JAN VIERENDEELS, SVEN SERBRUYNS, JOHN VANDE VOORDE   +3 more
doaj  

ON SOLVING PLANE PROBLEMS OF NON-STATIONARY HEAT CONDUCTION BY THE COLLOCATION BOUNDARY ELEMENT METHOD [PDF]

, 2017
D. Yu. Ivanov
openalex   +1 more source