Results 31 to 40 of about 167,985 (286)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Experimental Study on CoolingHeat Transfer of R410A and R22 in Small-diameter Tubes

Zhileng xuebao, 2020
A test rig for condensation heat transfer was developed and the cooling heat transfer characteristics of R22 and R410Ain small-diameter tubes were compared. The test conditions were as follows: the mass flow rate 200–800 kg/(m2?s), saturation temperature
Feng Guangdong, Liu Jianhua, Zhang Liang, He Kuan   +3 more
doaj  

The Experimental Study of Nanoparticles Effect on Thermal Efficiency of Double Pipe Heat Exchangers in Turbulent Flow [PDF]

Transport Phenomena in Nano and Micro Scales, 2014
In this work, the characteristics of flow and heat transfer of a fluid containing nano particles of aluminum oxide with the water volume fraction (0.1-0.2-0.3)(V/V) percent of the reports.
R. Aghayeri, H. Maddah, F. Ashori, M. Aghili   +3 more
doaj   +1 more source

Numerical investigation on flow and heat transfer characteristics of supercritical methane–ethane mixture in a straight channel

Science and Technology for Energy Transition, 2022
Printed Circuit Heat Exchanger (PCHE) is considered as a promising heat exchanger for offshore Liquefied Natural Gas (LNG) production due to its compactness and high efficiency.
Wang Yue, Li Yue, Chen Jie, Li Qian, Cai Weihua   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Local Heat Transfer Distribution and Effect of Instabilities During Flow Boiling in a Silicon Microchannel Heat Sink [PDF]

, 2011
Flow boiling of the perfluorinated dielectric fluid FC-77 in a silicon microchannel heat sink is investigated. The heat sink contains 60 parallel microchannels each of 100 lm width and 389 lm depth.
Garimella, Suresh V., Garimella, S V, Chen, Tailian, Tailian Chen, Suresh V. Garimella   +4 more
core   +1 more source

دراسة تجريبية لمبادل حراري صفائحي كمبرد هواء

Journal of Engineering
As cooling air using water injection was limited by a range of humidity ratio so indirect humidification for air consider, this research take the study of heat transfer through a perpendicular plate heat exchanger to discover the influence optimum ...
احمد أديب عبد الواحد
doaj   +1 more source

Experimental study of thermal performance in a rectangular finned-tube latent heat storage device with composite polyethylene wax/expanded graphite

Case Studies in Thermal Engineering, 2023
Phase change materials and geometric structure of latent heat storage (LHS) devices constitute crucial factors affecting the performance of phase change thermal energy storage systems.
Siyu Zheng, Songrui Li, Rui Dai, Mingshan Wei, Ran Tian, Panpan Song   +5 more
doaj   +1 more source