Results 41 to 50 of about 149,415 (317)

Study on Boiling Heat Transfer Characteristics of R290 in Horizontal Micro-tubes

Zhileng xuebao, 2020
In this study the boiling heat transfer characteristics of R290 in a 1, 2, and 4 mm horizontal micro-tube were investigated experimentally. The effects of mass flow rate [50-600 kg/(m2?s)], quality (0-1), and heat flux (5-20 kW/m2) on the boiling heat ...
Wang Haoyu, Liu Jianhua, Zhang Liang, Yu Xiaoxiao   +3 more
doaj  

Analytical considerations of flow boiling heat transfer in metal-foam filled tubes [PDF]

, 2012
Flow boiling in metal-foam filled tube was analytically investigated based on a modified microstructure model, an original boiling heat transfer model and fin analysis for metal foams.
Zhao, Changying, Tian, Y. (Yuan), Du, Y. P., Qu, Z. G.   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Activation Energy Impact on Flow of AA7072-AA7075/Water-Based Hybrid Nanofluid through a Cone, Wedge and Plate

Micromachines, 2022
The present research investigates the effect of a heat source/sink on nanofluid flow through a cone, wedge, and plate when using a suspension of aluminium alloys (AA7072 and AA7075) as nanoparticles in base fluid water.
Maaliger B. Rekha, Ioannis E. Sarris, Javali K. Madhukesh, Kondethimmanahalli R. Raghunatha, Ballajja C. Prasannakumara   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Tables for solution of the heat-conduction equation with a time-dependent heating rate [PDF]

, 1962
Tables are presented for the solution of the transient onedimensional heat flow in a solid body of constant material properties with the heating rate at one boundary dependent on time. These tables allow convenient and rapid estimation of the temperature
Bergles A. E.
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Design and Experimental Study on CO2 Water-cooled Tube-in-tube Gas Cooler

Zhileng xuebao, 2016
A water-cooled tube-in-tube gas cooler was designed in this paper, and experimental researches on it were conducted. A triple tube is equipped in the gas cooler with CO2 in the inner tubes and water between inner and outer tubes.
L, Jing, Ma Yiping, Cao Ke, Shi Dongdong, Gao Qiang, Hu Tete   +6 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

low Boiling Heat Transfer Characteristics of R290 in 5mm Small-diameter Tubes

Zhileng xuebao, 2019
The characteristics of heat transfer for R290 flow boiling in 5 mm small diameter tubes were investigated experimentally with a focus on the effects of heat flux, mass flow rate, and saturation temperature on the surface coefficient of boiling heat ...
He Kuan, Liu Jianhua, Yu Xiaoxiao
doaj