Results 41 to 50 of about 167,985 (286)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
, 2019 Heat and mass transfer is the core science for many industrial processes as well as technical and scientific devices. Automotive, aerospace, power generation (both by conventional and renewable energies), industrial equipment and rotating machinery ...
core +1 more source
Study on Boiling Heat Transfer Characteristics of R290 in Horizontal Micro-tubes
Zhileng xuebao, 2020 In this study the boiling heat transfer characteristics of R290 in a 1, 2, and 4 mm horizontal micro-tube were investigated experimentally. The effects of mass flow rate [50-600 kg/(m2?s)], quality (0-1), and heat flux (5-20 kW/m2) on the boiling heat ...
Wang Haoyu +3 more
doaj
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The influence of return bends on the downstream pressure drop and condensation heat transfer in tubes [PDF]
, 1971 The influence of return bends on the downstream pressure drop and heat transfer coefficient of condensing refrigerant R-12 was studied experimentally. Flow patterns in glass return bends of 1/2 to 1 in. radius and 0.315 in. I. D.
Traviss, Donald P., Rohsenow, Warren M.
core
Design and Experimental Study on CO2 Water-cooled Tube-in-tube Gas Cooler
Zhileng xuebao, 2016 A water-cooled tube-in-tube gas cooler was designed in this paper, and experimental researches on it were conducted. A triple tube is equipped in the gas cooler with CO2 in the inner tubes and water between inner and outer tubes.
L +6 more
doaj
Micromachines, 2022 The present research investigates the effect of a heat source/sink on nanofluid flow through a cone, wedge, and plate when using a suspension of aluminium alloys (AA7072 and AA7075) as nanoparticles in base fluid water.
Maaliger B. Rekha +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source