Results 61 to 70 of about 1,130,575 (394)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Литьë и металлургия, 2006 The system of measuring of the temperature fields distributing, constructed on the basis of digital camera-recorder, is considered. It is shown that the system has advantages as compared to traditional thermal-imaging sets on receivers, operating in ...
I. V. Fain +3 more
doaj
Applied Sciences, 2020 Cylinder-shaped fuel pellets that were 3 mm in diameter and 3 mm in height, with a mass of 20 mg, were produced by compressing dry coal processing waste under the pressure of 5 MPa. The first group of pellets from coal dust with a particle size less than
Dmitriy Klepikov +3 more
doaj +1 more source
Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2022 In present paper the influence of the boiling surface treatment types of thermosyphon evaporator on the heat transfer coefficient was studied. An experimental setup «Loop thermosyphon with replacing lower part of the evaporator» has been developed and ...
M. A. Kuzmich, A. A. Artsiukh
doaj +1 more source
Effect of surfactant on flow boiling heat transfer of ethylene glycol/water mixtures in a mini-tube [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +4 more
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
COMPLEX INVESTIGATIONS OF THERMALPHYSIC AND INFRA-RED CHARACTERISTICS AT THE PHASE INVERSIONS
Литьë и металлургия, 2005 The complex methods of investigation of heat exchange at crystallization and melting of selectively transparent materials in terms of changing of external heat influences, which include calorimetry of IK-currents, temperature taking, the heat conduction ...
V. L. Dragun +3 more
doaj
Fluids, 2021 The constant growth of urban agglomerations with the development of transport networks requires the optimal use of energy and new ways of storing it. Energy efficiency is becoming one of the main challenges of modern engineering.
Nadezhda S. Bondareva +1 more
doaj +1 more source
Atmospheric composition affects heat- and mass-transfer processes [PDF]
, 1970 For environmental control system functions sensitive to atmospheric composition, components are test-operated in helium-oxygen and nitrogen-oxygen mixtures, pure oxygen, and air.
Blakely, R. L., Nelson, W. G.
core +1 more source