Results 41 to 50 of about 450,750 (241)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Thermodynamic Properties of an Electron Gas in a Two-Dimensional Quantum Dot: An Approach Using Density of States

open access: yesQuantum Reports
Potential applications of quantum dots in the nanotechnology industry make these systems an important field of study in various areas of physics. In particular, thermodynamics has a significant role in technological innovations.
Luís Fernando C. Pereira   +1 more
doaj   +1 more source

CALCULATING THE MAGNETIC CONTRIBUTION TO THE HEAT CAPACITY OF THE QUASIONEDIMENSIONAL ISING MAGNETICS [PDF]

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2013
Effect of temperature, interactions up to three neighbors and sizes on heat capacity of small magnetic systems within the one-dimensional Ising model by Monte Carlo method was studied.
E.V. Shabunina   +3 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Saturated-liquid heat capacity: New polynomial models and review of the literature experimental data [PDF]

open access: yesJournal of the Serbian Chemical Society, 2003
In this paper a review of selected literature experimental data for saturated-liquid heat capacities was presented. Two-, three- and four-parameter polynomial correlation models are tested on those data.
Jovanović Jovan D.   +1 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

ANALYSIS OF THERMAL PROPERTIES OF THE LED-LINES BY METHOD OF ELECTRICАL TRANSIENT PROCESSES

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2015
Increasing the solid lighting facilities operational energy-efficiency in the national economy of the Republic of Belarus is of current concern. The modern problems of energy-saving lighting are multifaceted and broad-ranging.
S. A. Manеgo   +3 more
doaj  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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