Results 61 to 70 of about 1,658,583 (289)
Heat Capacity of Mesoscopic Superconducting Disks
We study the heat capacity of isolated giant vortex states, which are good angular momentum ($L$) states, in a mesoscopic superconducting disk using the Ginzburg-Landau (GL) theory.
Akkermans E. +6 more
core +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Shape- and topology-dependent heat capacity of few-particle systems
Thermal properties of few-fermion (n < 5) systems are investigated. The dependence of the heat capacity on the topology and shape of the cavity containing the particles is analyzed.
Barsan, Victor
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Exploring Criticality as a Generic Adaptive Mechanism
The activity of many biological and cognitive systems is not poised deep within a specific regime of activity. Instead, they operate near points of critical behavior located at the boundary between different phases.
Miguel Aguilera +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Absolute specific heat measurements of a microgram Pb crystal using ac nanocalorimetry
Heat capacity measurements using the ac steady state method are often considered difficult to provide absolute accuracy. By adjusting the working frequency to maintain a constant phase and using the phase information to obtain the heat capacity, we have ...
Rydh, A., Tagliati, S.
core +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Enhanced heat capacity and a new temperature instability in superfluid He-4 in the presence of a constant heat flux near T-lambda [PDF]
We present the first experimental evidence that the heat capacity of superfluid 4He, at temperatures very close to the lambda point Tλ, is enhanced by a constant heat flux Q.
Chatto, Andrew +5 more
core
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

