Results 101 to 110 of about 350,035 (281)

On Efficient Numerical Algorithms for Simulation of High Power Electrical Cables

open access: yesMathematical Modelling and Analysis, 2015
The new virtual modelling tool is constructed, which is used for optimal design of power transmission lines and cables. The construction of such lines should meet the latest power transmission network technical and economical requirements.
Raimondas Čiegis   +2 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Method of lines and finite difference schemes with the exact spectrum for solution the hyperbolic heat conduction equation

open access: yesMathematical Modelling and Analysis, 2011
This paper is concerning with the 1-D initial–boundary value problem for the hyperbolic heat conduction equation. Numerical solutions are obtained using two discretizations methods – the finite difference scheme (FDS) and the difference scheme with the ...
Harijs Kalis, Andris Buikis
doaj   +1 more source

Evaluation of thermal soak times [PDF]

open access: yes
A mathematical model for the heat transfer within the electronics package of a Chaparral missile was performed. The Grashof number for this configuration was less than 2000 which indicated that the primary mode of heat transfer was conduction.
Huddleston, H. P., Jr.   +1 more
core   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Heat Transfer in Granular Material: Experimental Measurements and Parameters Identification of Macroscopic Heat Conduction Model

open access: yesApplied Sciences
The paper presents experimental results regarding heat transfer in granular materials in the cylindrical domain during heating by the outer surface of the container.
Mariusz Ciesielski, Grzegorz Grodzki
doaj   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

The inverse stationary heat conduction problem for a cuboid

open access: yesMATEC Web of Conferences, 2017
The heat conductivity coefficient is important characteristic which is used in various spheres. The original methodic for conductivity coefficient determination was proposed for samples in form of rectangular parallelepiped.
Yacenko Konstantin M.   +2 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

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