Results 81 to 90 of about 1,698,755 (284)

Heat conduction in nanostructured materials

open access: yesJournal of Thermal Science and Technology, 2016
An overview of the direct and ab initio simulation as well as experimental tools addressing heat conduction in dielectric nanostructures and nanostructured materials is proposed.
Sebastian VOLZ   +3 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Tables for solution of the heat-conduction equation with a time-dependent heating rate [PDF]

open access: yes, 1962
Tables are presented for the solution of the transient onedimensional heat flow in a solid body of constant material properties with the heating rate at one boundary dependent on time. These tables allow convenient and rapid estimation of the temperature
Bergles A. E.
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

External heating of a flat plate in a convective flow [PDF]

open access: yes, 1984
The steady-state and íransient processes of the exteinal heating of a flat píate under a convective flow is studied in thís paper, with inclusión of the axial heat conduction tíirough the píate.
Treviño, César   +1 more
core  

Conduction of heat in inhomogeneous solids

open access: yes, 1998
In this letter we present a method for calculation of linear heat flow in inhomogeneous solids. The method is based on the evaluation of transfer matrices for each layer in a multilayered structure from the Laplace transformation of the partial ...
Dramicanin, Miroslav D.   +9 more
core   +1 more source

Research on the influencing factors of contact heat conduction between sliding rough surfaces

open access: yes矿业科学学报, 2019
The contact heat conduction problem between the rough sliding surfaces was studied through secondary development of finite element software ABAQUS.The thermal contact conductance was defined as a function of the sliding speed,the local contact pressure ...
Liu Yuwei   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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