Results 61 to 70 of about 366,602 (334)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Heat Transfer in Semitransparent Medium Caused by Laser Pulse

International Journal of Industrial Engineering and Production Research, 2008
In this paper, the combination of conduction with radiation into a semitransparent medium which includes absorption, emission and scattering has been investigated.
E . Izadpanah, A . Akhavan Taheri, M . H Hekmat, S . Talebi   +3 more
doaj  

Effect of electrically aligned polycrystalline diamond flakes on the through-plane thermal conductivity of heat conduction sheets

Functional Diamond
Heat conduction sheets, which are composed of a thermally conductive filler and a base elastomer matrix, are important for dissipating heat from devices to a heat sink.
Masafumi Inaba, Seiya Seike, Yingchen Chen, Soichiro Ichiki, Yoshihiko Kubota, Shinya Ohmagari, Michihiko Nakano, Junya Suehiro   +7 more
doaj   +1 more source

Freezing of Biological Tissues During Cryosurgery Using Hyperbolic Heat Conduction Model

Mathematical Modelling and Analysis, 2015
This paper considers hyperbolic heat conduction model for biological tissue freezing during cryosurgery with non ideal property of tissue, metabolism and blood perfusion.
Sonalika Singh, Sushil Kumar
doaj   +1 more source

Implicit adaptation of mesh model of transient heat conduction problem [PDF]

, 2022
Zhukov Petr, Anton Glushchenko, Fomin Andrey   +2 more
openalex   +1 more source

Thermal conduction in molecular chains: Non-Markovian effects

, 2008
We study the effect of non-Markovian reservoirs on the heat conduction properties of short to intermediate size molecular chains. Using classical molecular dynamics simulations, we show that the distance dependence of the heat current is determined not ...
Ashcroft N. W., Dvira Segal
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Explicit Time Integration Method Based on Uniform Trigonometric B-Spline Function for Transient Heat Conduction Analysis

Applied Sciences
In this paper, a new explicit time integration method for transient heat conduction analysis is proposed based on the uniform trigonometric B-spline function. The algorithmic calculation procedure for solving the heat conduction problem is given.
Zixu Li, Yongyu Hong, Pan Wang, Weibin Wen   +3 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source