Results 51 to 60 of about 366,602 (334)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Heat Conduction in Porous Media Characterized by Fractal Geometry

open access: yesEnergies, 2017
Fractal geometry (fractional Brownian motion—FBM) is introduced to characterize the pore distribution of porous material. Based on this fractal characterization, a mathematical model of heat conduction is presented to study heat conduction behaviors in ...
Zilong Deng   +4 more
doaj   +1 more source

Influence of extended heat sources on the temperature distribution in profiled polar-orthotropic annular plates with heat-insulated bases

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2021
The solution of the stationary heat conduction problem for profiled polar-orthotropic annular plates with heat-insulated bases from N extended heat sources at their external border is presented.
Uladzimir V. Karalevich   +1 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Heat conduction in 2D strongly-coupled dusty plasmas

open access: yes, 2008
We perform non-equilibrium simulations to study heat conduction in two-dimensional strongly coupled dusty plasmas. Temperature gradients are established by heating one part of the otherwise equilibrium system to a higher temperature. Heat conductivity is
Alexander Piel   +2 more
core   +1 more source

Electron and proton heating by solar wind turbulence [PDF]

open access: yes, 2009
Previous formulations of heating and transport associated with strong magnetohydrodynamic (MHD) turbulence are generalized to incorporate separate internal energy equations for electrons and protons. Electron heat conduction is included.
B. Breech   +49 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Hot bubbles of planetary nebulae with hydrogen-deficient winds I. Heat conduction in a chemically stratified plasma

open access: yes, 2015
Heat conduction has been found a plausible solution to explain discrepancies between expected and measured temperatures in hot bubbles of planetary nebulae (PNe).
Rühling, Ute   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Heat guiding and focusing using ballistic phonon transport in phononic nanostructures

open access: yesNature Communications, 2017
Heat conduction at the nanoscale is unlike macroscopic diffusion and phonons can travel in straight lines without dissipation. Here Anufrievet al. show that heat conduction can be spatially directed in nanostructured silicon and exploit this effect to ...
Roman Anufriev   +3 more
doaj   +1 more source

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