Results 71 to 80 of about 62,842 (255)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The Self-limiting Nature of Jet-modulated Thermal Conduction in Cool Core Clusters

The Astrophysical Journal
Conduction as a mechanism for explaining the disrupted cooling-flow in galaxy clusters has been mostly discounted, as the process is inefficient at transporting heat all the way from the cluster into the core.
Jennifer N. Stafford, Sebastian Heinz, Mateusz Ruszkowski, Torsten Enßlin, Yi-Hao Chen   +4 more
doaj   +1 more source

Effect of Gradient Heat Conduction on Secondary Recrystallization of Grain-Oriented Silicon Steel

Metals
The grain-oriented silicon steels were subjected to gradient heat conduction during high-temperature annealing by using thermal insulation cotton. The macrostructures of samples subjected to circumferential gradient heat conduction showed a “petal-like ...
Qian Gao, Xianhui Wang, Jun Li, Laifu Cao, Jian Gong, Bo Li   +5 more
doaj   +1 more source

Shape sensitivity for a two-phase heat conduction problem considering nanoscale effects

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
Thermal design is essential when developing various types of technological devices, especially miniaturized electronic devices. Conventional thermal design methods that only focus on macrostructures can provide only limited improvements in electronic ...
Kozo FURUTA, Ayami SATO, Kazuhiro IZUI, Mitsuhiro MATSUMOTO, Takayuki YAMADA, Shinji NISHIWAKI   +5 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Research on mitigation strategies for axial heat conduction in cryogenic microchannel heat exchangers

Case Studies in Thermal Engineering
The compact design of microchannel heat exchangers (MCHX) offers significant advantages for their utilization in cryogenic systems, but it is accompanied by serious axial heat conduction problems.
Tao Zhu, Xiaoli Duan, Bingcheng Wang, Cheng Shao, Zheng Cui   +4 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Fractional single-phase-lagging heat conduction model for describing anomalous diffusion

Propulsion and Power Research, 2016
The fractional single-phase-lagging (FSPL) heat conduction model is obtained by combining scalar time fractional conservation equation to the single-phase-lagging (SPL) heat conduction model.
T.N. Mishra, K.N. Rai
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source