Results 71 to 80 of about 1,698,755 (284)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Feature extraction via heat flow analogy
, 2009 Feature extraction is an important field of image processing and computer vision. Features can be classified as low-level and high-level. Low-level features do not give shape information of the objects, where the popular low-level feature ...
Direkoğlu, Cem
core +1 more source
Radial conduction effects in transient heat transfer experiments [PDF]
, 1997 [Introduction]: Convective heat transfer data is frequently obtained from transient surface temperature measurements. Thin film resistance gauges, thermocouples, and thermochromic liquid crystals, are used in various situations to measure the surface ...
Jones, T. V., Buttsworth, David R.
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Partial Differential Equation for Heat Conduction and Its Solvability
, 2010 This paper deals with the heat conduction equation which is a model of thermomechanical processes in the special case.
Ondrej Kovacik, Pavol Orsansky
core +1 more source
The Behavior of Heat Flow and Temperature under Quantum-Relativistic Conditions [PDF]
Journal of Heat and Mass Transfer ResearchIn this article, the effect and behaviour of ultra-high-velocity heat motion are described. The ultra-high velocity of heat conduction in a system composed of particles in gas form is viewed as the motion of particles that aligns with the principles of ...
Arezu Jahanshir
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
EnergiesIn this study, the influence of residual gas pressure within a vacuum insulation cavity on the insulation performance of a multi-layer insulation (MLI) system was investigated through thermal analysis. Based on an electrical analogy, a thermal resistance
Tae Yun Lee, Jeong Soo Kim
doaj +1 more source