Results 141 to 150 of about 189,544 (307)

Comparison of Earth-Air and Earth-Water Ground Tube Heat Exchangers for Residentialal Application

open access: yes, 2012
Earth-air systems are already commonly applied as a passive technique to reduce the overall energy use of buildings by reducing the required cooling or heating demand. However, they often require large surface area for their installation, and make use of
Liu, Liping   +2 more
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Enabling Demand Side Management: Heat Demand Forecasting at City Level. [PDF]

open access: yesMaterials (Basel), 2019
Hietaharju P, Ruusunen M, Leiviskä K.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

‘Greening’ the UK: A Comparative Study of Heat Pumps and Hydrogen Boilers in Residential Heating

open access: yesEnergies
With a key policy decision on the role of hydrogen boilers expected by 2026, the UK is at a strategic crossroads in implementing its Heat and Buildings Strategy.
Lin Gao   +3 more
doaj   +1 more source

Time series analysis of heat demand

open access: yes, 2011
The paper deals with an analysis of time series of heat demand course. The course of heat demand and heat consumption can be demonstrated by means of heat demand diagrams.
Chramcov, Bronislav, Balátě, Jaroslav
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

A Simulation Tool for Radiative Heat Exchangers

open access: yes, 2012
In order to minimize the large fan power demand from low temperature lift heat pump systems, a radiative heat exchanger is proposed as an indoor heat exchanger design in such systems.
Radermacher, Reinhard   +2 more
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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