Results 31 to 40 of about 1,688,117 (284)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
HEAT EXHAUSTION AND EXERTIONAL HEATSTROKE
Pakistan Armed Forces Medical Journal, 2007 Introduction Heat illness is a major cause of preventable morbidity worldwide, especially in regions characterized by high ambient temperatures.
Dilshad Ahmed Khan, Muhammad Aslam
doaj +2 more sources
Heat Stress Management in Broilers
EDIS, 2018 High ambient temperatures can be devastating to commerical broilers; coupled with high humidity they can have an even more harmful effect. Heat stress interferes with the broilers comfort and suppresses productive efficiency.
Gary D. Butcher, Richard Miles
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
, 2016 In this chapter, I address the relationship between the principle of trademark exhaustion and the free movement of goods in free trade areas. In particular, I analyze the existing approaches to trademark exhaustion and parallel imports in the following ...
Calboli, Irene
core +2 more sources
Assessment of two-level heat pump installations’ power efficiency for heat supply systems
Trudy Odesskogo Politehničeskogo Universiteta, 2015 The problem of energy saving becomes one of the most important in power engineering. It is caused by exhaustion of world reserves in hydrocarbon fuel, such as gas, oil and coal representing sources of traditional heat supply.
Алла Євсеївна Денисова +1 more
doaj +7 more sources
Health impact of climate change on occupational health and productivity in Thailand
Global Health Action, 2010 Background: The rise in global temperature is well documented. Changes in temperature lead to increases in heat exposure, which may impact health ranging from mild heat rashes to deadly heat stroke.
Sasitorn Taptagaporn +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
Experimental determination of natural convection heat transfer coefficients in an attic shaped enclosure [PDF]
, 2010 Heat transfer by natural convection in triangular enclosures is an area of significant importance in applications such as the design of greenhouses, attics and solar water heaters.
Carson, James K. +5 more
core +1 more source