Results 131 to 140 of about 182,887 (314)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Computational modelling of the HyperVapotron cooling technique for nuclear fusion applications [PDF]

, 2010
Efficient heat transfer technologies are essential for magnetically confined fusion reactors; this applies to both the current generation of experimental reactors as well as future power plants.
Milnes, Joseph
core  

Unsteady Marangoni convection heat transfer of fractional Maxwell fluid with Cattaneo heat flux

, 2017
Highlights\ud \ud • Unsteady Marangoni convection heat transfer of viscoelastic fluid over flat surface with variable heat flux are investigated.\ud \ud • Fractional shear stress and Cattaneo heat flux models are introduced firstly in ...
Zhao, Jinhu, Liu, Fawang, Liancun Zheng, Xinxin Zhang, Chen, Xuehui, Zheng, Liancun, Jinhu Zhao, Zhang, Xinxin, Xuehui Chen, Fawang Liu   +9 more
core   +1 more source

Error Analyses for the Frequently-Used Calorimeters in Arc Jet

气体物理
The slug calorimeter, the improved slug calorimeter and the water calorimeter are usually chosen to measure the heat flux values on the model surface based on the magnitude of heat flux values.
Kao XU, Lianzhong CHEN, Zhiming CHEN, Dongbin OU   +3 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

The influence of return bends on the downstream pressure drop and condensation heat transfer in tubes [PDF]

, 1971
The influence of return bends on the downstream pressure drop and heat transfer coefficient of condensing refrigerant R-12 was studied experimentally. Flow patterns in glass return bends of 1/2 to 1 in. radius and 0.315 in. I. D.
Traviss, Donald P., Rohsenow, Warren M.
core  

Effect of heat flux on pitting and passive film of 304SS in 3.5 wt.% NaCl solution

npj Materials Degradation
In this work, the effect of heat flux on pitting corrosion behaviors and passive film properties of 304 stainless steel in 3.5 wt.% NaCl solution were investigated by the self-developed metal heat transfer surface testing system using electrochemical ...
Ze-Yu Zhou, Bo-Kai Liao, Kai Qi, Yu-Bing Qiu, Zhen-Yu Chen, Xing-Peng Guo   +5 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

HIGH-HEAT-FLUX RESISTANCE HEATERS FROM VPS AND HVOF THERMAL SPRAYING

, 1998
This article describes the application of thermal spray techniques to produce resistance heating elements suitable for applying very large heat flaxes to solid surfaces.
J. Hadeler, D. Michels, Lienhard, John H, J.H. Lienhard V, Hadeler, J., Michels, D.   +5 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source