Results 41 to 50 of about 701,963 (354)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Development of heat flux sensors in turbine airfoils [PDF]
, 1984 The objective is to develop heat flux sensors suitable for use on turbine airfoils and to verify the operation of the heat flux measurement techniques through laboratory experiments.
Atkinson, W. H., Strange, R. R.
core +1 more source
IEEE Access, 2019 Inconel 718 has been taken as the difficult-to-machine material for manufacturing aerial turbine disk due to its superior high-temperature resistance and high hardness. Massive heat flux generated at the tool-chip interface, and high tool temperature can
Jinfu Zhao, Zhanqiang Liu
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
3D modeling of n = 1 RMP driven heat fluxes on the SPARC tokamak PFCs using HEAT
Nuclear Fusion3D heat flux calculations at the lower outer divertor plate of SPARC using the HEAT code show that 3D fields generated from error field correction coils can lead to enhanced peak heat fluxes up to 15 times larger compared to the axisymmetric case ...
M. Scotto d’Abusco +7 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
HEAT simulation and IR data comparison for ST40 plasma-facing components
Nuclear Materials and EnergyThe Heat Flux Engineering Analysis Toolkit (HEAT) (Looby et al., 2022) was used to simulate the heat flux, qtarget, on ST40 molybdenum divertors. Results were compared with experimental infrared (IR) data.
E.J.C. Tinacba +10 more
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
What determines the distribution of shallow convective mass flux through cloud base?
, 2017 The distribution of cloud-base mass flux is studied using large-eddy simulations (LES) of two reference cases, one representing conditions over the tropical ocean, and another one representing mid-latitude conditions over land.
Hohenegger, Cathy, Sakradzija, Mirjana
core +1 more source
Energies, 2022 Concentrating photovoltaic power generation technology is a highly efficient way of utilizing solar energy resources with the efficiency limited by cell cooling conditions.
Qi Yang +5 more
doaj +1 more source