Results 61 to 70 of about 685,387 (303)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
An estimate of the surface heat fluxes transfer of the Persian Gulf with the overlying atmosphere
Journal of Radiation Research and Applied Sciences, 2015 The ocean heat exchange process is a key mechanism in climate variations over a broad time – scale. In this study, the long–term mean surface heat fluxes over the Persian Gulf have been estimated by the empirical relations using data derived from ...
A. Rezaei-Latifi, F. Hosseinibalam
doaj +1 more source
Thermal Diode: Rectification of Heat Flux [PDF]
Physical Review Letters, 2004 4 pages, 5 figs in publication ...
Li, B., Wang, L., Casati, G.
openaire +4 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Flow boiling heat transfer of refrigerant R-134a in copper microchannel heat sink [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +2 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Model Investigation of Subcooled Flow Boiling in Narrow Rectangular Channel Using CFD Method
Yuanzineng kexue jishu, 2022 The plate-type fuel assembly with the advantages of high specific power of active zone and compact structure has been widely adopted in many research reactors and material irradiation test reactors.
LIU Kai;LI Linfeng;WANG Mingjun;ZHANG Jing;TIAN Wenxi;QIU Suizheng;SU Guanghui
doaj
Effect of torch angle on arc properties and weld pool shape in stationary GTAW [PDF]
, 2013 In this paper, a three dimensional numerical simulation is performed on a stationary arc to study the effect of torch angle in gas tungsten arc welding (GTAW) of SS304 stainless steel.
Abid, Muhammad +4 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Wall heat flux measurements in a GO2/GH2 heat-sink combustion chamber
Journal of Thermal Science and Technology, 2018 In order to understand heat transfer mechanisms in the combustion chamber with multi-elements injector and provide benchmark data of wall heat fluxes for the CFD code validation, experiments were carried out in a GH2/GO2 heat-sink combustion chamber.
Taiping WANG +3 more
doaj +1 more source