Results 81 to 90 of about 182,887 (314)

Estimation of Sensible and Latent Heat Fluxes from Different Ecosystems Using the Daily-Scale Flux Variance Method

Atmosphere
A daily-scale flux variance (FV) method, which employs low-frequency air temperature measurements, was assessed against eddy covariance (EC) measurements of sensible and latent heat fluxes at four sites representing grassland and cropland ecosystems. The
Yanhong Xie, Jingzheng Xu, Yini Pu, Lei Huang, Mi Zhang, Wei Xiao, Xuhui Lee   +6 more
doaj   +1 more source

Application of the Critical Heat Flux Look-Up Table to Large Diameter Tubes

Science and Technology of Nuclear Installations, 2013
The critical heat flux look-up table was applied to a large diameter tube, namely 67 mm inside diameter tube, to predict the occurrence of the phenomenon for both vertical and horizontal uniformly heated tubes. Water was considered as coolant.
M. El Nakla, M. Habib, W. Ahmed, A. Al-Sarkhi, R. Ben Mansour, M. Y. Al-Awwad   +5 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

PREDICTION OF TWO-PHASE FLOW BOILING CHARACTERESTICS IN MICROCHANNELS HEAT SINK BY ARTIFICIAL NEURAL NETWORK

Journal of Engineering and Sustainable Development, 2017
The current study investigated flow boiling heat transfer, pressure drop in a copper multi-parallel microchannels heat sink using R134a as a working fluid.
Adnan A. Abdulrasool, Ekhlas M. Fayyadh , Adil Abbas Mohammed   +2 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Parametric effects on dryout of propane in a vertical circular mini-channel

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Palm, B, Khodabandeh, R, Maqbool, MH, 3rd Micro and Nano Flows Conference (MNF2011)   +3 more
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Experimental investigation of non-uniform heating on flow boiling instabilities in a microchannels based heat sink

, 2009
Two-phase flow boiling in microchannels is one of the most promising cooling technologies able to cope with high heat fluxes generated by the next generation of central processor units (CPU).
Bogojevic, D, Cummins, G, Lin, H., H. Lin, D. Bogojevic, K. Sefiane, G. Cummins, T. G. Karayiannis, Lin, H, Sefiane, K, Sefiane, K., Walton, AJ, Cummins, G.; id_orcid, Bogojevic, D., Kenning, D.B.R., D. B. R. Kenning, Karayiannis, TG, Kenning, DBR, A. J. Walton, Karayiannis, T.G., Walton, A.J.   +20 more
core   +1 more source

Near-surface ocean temperature and air-sea heat flux observed by a buoy array during summer to autumn in year 2014 in the northern South China Sea

Frontiers in Marine Science
The observational data of the air-sea interface and upper ocean elements from a buoy array deployed in the northern South China Sea from June to November 2014 is analyzed.
Zixi Wu, Han Zhang, Han Zhang, Han Zhang
doaj   +1 more source