Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Heat Transfer Augmentation and Entropy Generation Analysis of Microchannel Heat Sink (MCHS) with Symmetrical Ogive-Shaped Ribs [PDF]
This study proposes the use of symmetrical ogive-shaped ribs on the walls of microchannel heat sinks (MCHS) to improve their thermal performance with minimal pressure drop.
Zahir, Muhammad Zeeshan +17 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Evaluating the Role of Entropy Change in Lithium-Ion Battery Electro-Thermal Modelling
The accurate estimation of lithium-ion cell internal temperature is crucial for the safe operation of battery packs, especially during high discharge rates, as operating outside the safe temperature range can lead to accelerated degradation or ...
Félix-Antoine LeBel +3 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Using the Lattice Boltzmann Method for the numerical study of non-fourier conduction with variable thermal conductivity [PDF]
The lattice Boltzmann method (LBM) was used to analyze two-dimensional (2D) non-Fourier heat conduction with temperature-dependent thermal conductivity. To this end, the evolution of wave-like temperature distributions in a 2D plate was obtained.
AhmadReza Rahmati, A. Gheibi
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A novel, new generation drill coating for osteotomy site preparation
Background: Implant success and survival rate ranges from 93% to 97%; however, failures are not very uncommon. These failures can be caused due to a variety of reasons out of which increased heat during drilling of osteotomies is a major contributor.Aim:
Pooja P Wadkar +5 more
doaj +1 more source
This paper studies convective heat transfer in an unsteady vertical porous channel with suction/injection in the presence of heat generation. A semi-implicit finite difference method was employed to solve the Cartesian coordinate forms of the governing ...
Adebowale Martins Obalalu +2 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

