Results 71 to 80 of about 1,077,007 (312)

The unlikely Carnot efficiency

open access: yes, 2014
The efficiency of an heat engine is traditionally defined as the ratio of its average output work over its average input heat. Its highest possible value was discovered by Carnot in 1824 and is a cornerstone concept in thermodynamics.
Broeck, Christian Van den   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Welding input effect on the corrosion behavior and microstructure of heat treated GTAW welds of Inconel 718

open access: yesInternational Journal of Electrochemical Science, 2019
The susceptibility to corrosion of Inconel 718 weldments after double aging heat treatment was studied by the use of potentiodynamic tests. Plates of 3 mm thick were homogenized at 1080 °C during 1 hour and air cooled, then subjected to a solution ...
M.L. Hernández-Rodríguez   +4 more
doaj   +1 more source

Experimental and numerical analysis of intermetallics in Al–Mg friction stir welds

open access: yesMaterials Research Express, 2023
In this research work, it was aimed to analyse the thermal behaviour during FSW in order to understand the diffusion behaviour of Al (AA6061)-Mg (AZ31B) dissimilar joints. Three heat input levels at different weld pitch ratios (WPR) of 0.087, 0.068 and 0.
M Naveenkumar, M Subramanian, R Ranjith
doaj   +1 more source

Passive heat transfer control [PDF]

open access: yes, 1970
Model maintains a preselected temperature in the near vicinity of a variable source of thermal energy. Heat input is controlled by a variable transformer and a voltage drop across the heater is used to calculate power ...
Fitz, F. A.
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Multichamber controllable heat pipe [PDF]

open access: yes, 1970
Valve throttles transfer of vapor between heat input surface and heat rejection surface of heat pipe to control rate of transfer of energy.
Shlosinger, A. P.
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

ANALISIS KINERJA KOMPOR GAS BERBAHAN BAKAR DIMETHYL ETHER DENGAN VARIASI DIAMETER LUBANG ANGIN PADA NOSEL

open access: yesRekayasa Mesin
The use of a vent on a gas stove affects the mixing of air with fuel. This study examines the effect of different vent diameters on the performance of Dimethyl Ether (DME) gas-fueled stoves.
Seno Sutrisno   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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