Results 71 to 80 of about 231,992 (267)

Artificial neural network modelling of cold-crack resistance of high strength low alloy steel 950A

open access: yesThe Journal of Engineering, 2019
The objective of the study is to predict the cold cracking resistance of high strength low alloy 950A welded joints using an artificial neural network (ANN) model. A bead on plate welding is carried out using the gas metal arc welding process.
Velumani Manivelmuralidaran   +1 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Effects of Heat Input on the Mechanical and Metallurgical Characteristics of Tig Welded Incoloy 800Ht Joints

open access: yesArchives of Metallurgy and Materials, 2017
This study focuses on the effect of heat input on the quality characteristics of tungsten inert arc gas welded incoloy 800HT joints using inconel-82 filler wire.
Kumar S. Arun, Sathiya P.
doaj   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Research on Mechanical Properties of Non-Directly Welded Reinforced Casings Under High Stress Ratio

open access: yesBuildings
Aiming at the requirement of high stress ratio reinforcement in space steel structures, a novel method for enshancing the load-bearing capacity of casings through indirect welding to produce a reinforced steel pipe is introduced.
Yiwei Fang   +3 more
doaj   +1 more source

Effect of Welding Heat Input on the Microstructure and Toughness in Simulated CGHAZ of 800 MPa-Grade Steel for Hydropower Penstocks

open access: yesMetals, 2017
To determine the appropriate welding heat input for simulated coarse grained heat affected zone (CGHAZ) of 800 MPa-grade steel used in hydropower penstocks, the microstructural evolution, hardness, and 50% fraction appearance transition temperature (50 ...
Qingfeng Ding   +5 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Microstructural, Mechanical, and Electrochemical Analysis of Duplex and Superduplex Stainless Steels Welded with the Autogenous TIG Process Using Different Heat Input

open access: yesMetals, 2017
Duplex Stainless Steels (DSS) and Superduplex Stainless Steels (SDSS) have a strong appeal in the petrochemical industry. These steels have excellent properties, such as corrosion resistance and good toughness besides good weldability. Welding techniques
Gláucio Soares da Fonseca   +4 more
doaj   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

open access: yesArthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni   +7 more
wiley   +1 more source

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