Results 201 to 210 of about 234,935 (316)
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
Cytoskeleton, EarlyView.ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
Cytoskeleton, EarlyView.ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen +2 more
wiley +1 more source
Stability of Viscous Three‐Dimensional Stratified Couette Flow via Dispersion and Mixing
Communications on Pure and Applied Mathematics, EarlyView.ABSTRACT This article explores the stability of stratified Couette flow in the viscous 3d$3d$ Boussinesq equations. In this system, mixing effects arise from the shearing background, and gravity acts as a restoring force leading to dispersive internal gravity waves.
Michele Coti Zelati +2 more
wiley +1 more source
Deep Underground Science and Engineering, EarlyView.Abstract As tunnel construction advances in lengths and depths, the construction of tunnels in high geothermal environments has become increasingly common, raising significant fire risks. In this study, a 1:20 scale model tunnel test platform was constructed to investigate the effects of a high geothermal environment on fire behavior in tunnels during ...
Xiaoxian Fei +6 more
wiley +1 more source
An assessment of stress and production rate of sucker rod heat pipes in oil well pumping system
Deep Underground Science and Engineering, EarlyView.The sucker rod pumping system is the preferred oil extraction technique. The concept about equipping the hollow vacuum space in solid sucker rods with heat pipe has been scrutinized in terms of stress and oil production evaluation. Abstract The implementation of the heat pipe concept in sucker rods for oil pumping systems negates the requirement for an
R. S. Anand +5 more
wiley +1 more source
Deep Underground Science and Engineering, EarlyView.Our study reveals that caving‐enhanced geothermal systems (C‐EGS) with adequately fractured reservoirs achieve optimal heat extraction by minimizing preferential flow paths, while conventional fracturing (F‐EGS) and pipe‐based (P‐EGS) systems suffer accelerated thermal drawdown.
Fangchao Kang +4 more
wiley +1 more source
Deep Underground Science and Engineering, EarlyView.This paper explores how climate‐resilient technologies, such as smart grids, digital twins, and self‐healing materials, can enhance urban resilience. It highlights the urgent need for proactive planning, public‐private collaboration, and data‐driven innovation to future‐proof underground infrastructure amid accelerating climate and urban pressures ...
Kai Chen Goh +12 more
wiley +1 more source
Deep Underground Science and Engineering, EarlyView.The evolution of the temperature field and frozen wall under different fracture conditions was examined by an artificial ground freezing‐based thermal‐hydraulic coupled model. It was observed that fracture inclination affects the interaction extent of freezing pipes and fracture, while phase transition extent is the dominant factor for heat transfer in
Chenyi Zhang +9 more
wiley +1 more source
Deep Underground Science and Engineering, EarlyView.Aluminum‐enhanced afterburning renders AE explosives more hazardous than conventional ones. Corrugated steel linings reduce far‐field AE blast overpressure by ~50% through wave reflection and dissipation. The developed model accurately predicts peak pressure (<10% error) and arrival time (<3% error), supporting protective design.
Zhen Wang +5 more
wiley +1 more source