Results 41 to 50 of about 501,521 (263)

Conjugate heat dissipation characteristics of concurrent flow of pure water/water-based nano-emulsion through a mini- and micro-channel stacked double-layer heat sink

Case Studies in Thermal Engineering
The main purpose of current study is to reduce the temperature gradient and pressure drop in the heat sinks by using a new double-layer mini/micro-channel stacked heat sink.
C.J. Ho, Jr-Wei Liao, Bo-Lin Chen, Saman Rashidi, Wei-Mon Yan   +4 more
doaj   +1 more source

Numerical Investigation of the Double Diffusive Convection in 3D Trapezoidal Solar Still Equipped with Conductive Fins

Mathematics, 2022
In this paper a numerical investigation on the double diffusive natural convection in a finned solar still is performed using the finite volume method. The 3D vector potential-vorticity formalism is used to eliminate the gradient pressure terms and due ...
Lioua Kolsi, Kaouther Ghachem, Samia Larguech, Ghada AlNemer   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Numerical Study on Turbulent Forced Convection and Heat Transfer Characteristic in a Circular Tube with V-Orifice

Modelling and Simulation in Engineering, 2017
Performance assessments on heat transfer, pressure loss, and thermal enhancement factor in the circular tube heat exchanger inserted with the V-orifices are investigated numerically.
Withada Jedsadaratanachai, Amnart Boonloi   +1 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Validation of PCHE-Type CO₂–CO₂ Recuperative Heat Exchanger Modeling Using Conductance Ratio Method

Energies
Printed-circuit heat exchangers (PCHEs) are compact exchangers with exceptional heat-transfer properties that are important for supercritical CO2 technology. Recalculating the heat transfer under off-design conditions is a common task.
Viktoria Carmen Illyés, Francesco Crespi, Xavier Guerif, Andreas Werner   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Thermal performance analysis of heat pipe using response surface methdology

Journal of Thermal Engineering, 2023
Heat pipes are the specific class of heat exchangers. They are used in thermal management of electronic components. Research community is continuously working to obtain the optimum heat transfer performance. In present work, parametric study of heat pipe
Udayvir SINGH, Naveen Kumar GUPTA
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source