Results 61 to 70 of about 501,521 (263)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Gas Consumption Accounting and Prediction for Medium and Thick Steel Slabs: A Method Combining Batch Integrity and Heat Absorption Ratio

International Journal of Computational Intelligence Systems
The heating process of steel slabs is a critical stage in the production of medium and thick plates, significantly impacting production costs and energy efficiency. Existing research faces two major scientific challenges in gas consumption accounting and
Qiang Guo, Xinyu Liang, Kai Wang, Yong Song   +3 more
doaj   +1 more source

Multi layer heat conduction analysis using SPH method

Nihon Kikai Gakkai ronbunshu, 2016
Smoothed particle hydrodynamics (SPH) is a particle method for analyzing physical problems. But this method has numerical problems when treating multilayer problems and free surface. In this report we propose equations to treat multilayer heat conduction
Naohiro MATSUMOTO, Toru OKUNO, Haruki OBARA, Tohru SASAKI   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Convective heat transfer characterization for novel hybrid lattice structures based on triply periodic minimal surfaces

Case Studies in Thermal Engineering
Triply periodic minimal surfaces (TPMS) show superior advantages for efficient thermal management of heat exchanger because of high area-to-volume ratio and excellent overall heat transfer performance.
Zijian Zhang, Zhengying Wei, Junfeng Li
doaj   +1 more source

Bowen Ratio Method for Measuring Heat Transfer on Land Cover Change in Establishing Green Patch in Urban Heat Island of Bangkok

Modern Applied Science, 2014
Due to the rapid growth of urban heat island (UHI) in Bangkok, which is covered by 1,568.7 sq.km and 1.5 mMSL and surrounded by the Gulf of Thailand and Chao Phraya river, has been gradual.ly extended through suburban areas that making ambient air temperature increased about 0.03 °C/y for 56-year period (1957 to 2013).
Alongkorn Intaraksa, Kasem Chunkao, Surat Bualert   +2 more
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Influence of Fin Spacing and Fin Height in Passive Heat Sinks: Numerical Analysis with Experimental Comparison

Applied Sciences
In this paper, heat dissipation through a passive vertical plate fin heat sink via natural convection was numerically investigated. The influence of two nondimensional geometric parameters, fin spacing-to-thickness ratio and fin height-to-spacing ratio ...
Mateo Kirinčić, Tin Fadiga, Boris Delač   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source