Results 121 to 130 of about 11,123,934 (324)

NS1‐Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication

Advanced Science, EarlyView.
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma, Changyuan Kang, Xixian Liu, Lichao Yang, Mengyi Li, Yuting Ye, Jianfang Zhang, Yingjun Li, Guanghui Jin, Yang Liu, Xiaohong Chen, Kexin Wang, Zifeng Yang   +12 more
wiley   +1 more source

Solvent‐Free Synthesis of Ultrabright Carbon Dots With Near‐Unity Quantum Yield for High‐Performance Light‐Emitting Diodes

Advanced Science, EarlyView.
A rational, solvent‐free synthesis utilizing 2,6‐diaminonaphthalene produces ultrabright green‐emissive carbon dots. Regulated by a self‐limiting oxidative capping mechanism, excitons undergo ultrafast intra‐particle funneling from the nitrogen‐doped carbon core to emissive surface traps.
Hyeonjin Park, Su Hwan Lee, Sejeong Seo, Soye Park, Soo min Ji, Hyunda Jo, Sehyeon Park, Young‐Hoon Kim, Woosung Kwon   +8 more
wiley   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Dog owners’ perceptions and behaviors regarding extreme heat and weather events

Human-Animal Interactions
Extreme heat and environmental disasters pose significant threats to canine health and welfare. With climate change intensifying these hazards and approximately 59.9 million U.S.
Ashley Etue, Lori R. Kogan, Emma Brown
doaj   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

Does wearing a breathable T-shirt improve the microclimate and thermoregulatory responses during a hot outdoor running?

Fashion and Textiles
Clothing hinders heat and moisture transfer from the skin to the environment, potentially disrupting thermoregulation during exercise in hot conditions.
Hanano Kato, Yumi Okamoto, Junto Otsuka, Shotaro Yokoyama, Shoma Oshima, Kazuya Tajima, Atsushi Shiraishi, Ai Shiramoto, Tatsuro Amano   +8 more
doaj   +1 more source

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

Advanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye, Miaoru Han, Siqiao Tang, Zongxiang Zhang, Haichen Shen, Bingzhen Sun, Yan Zhang, Xiaodong Chu, Lijuan Deng, Chaoyang Zheng, Qingchun Huang, Kun Bao, Ronghua Zhang, Yong Wang, Fengwei Zhang, Xiaoli Chu   +15 more
wiley   +1 more source

Probe‐Free, Primer‐Programmed Amplicon Encoding Enables Nanopore‐Based Multiplex Detection With Deep Learning Decoding

Advanced Science, EarlyView.
Primer‐programmed amplicon encoding enables reporter‐probe‐free multiplex nucleic acid identification using glass nanopore sensing and deep neural network decoding. ABSTRACT Single‐reaction multiplex nucleic acid testing (NATs) must both co‐amplify multiple targets and distinguish the resulting amplicons within the product mixture.
Md. Ahasan Ahamed, Muhammad Asad Ullah Khalid, Wahid Uz Zaman, Anthony J. Politza, Weihua Guan   +4 more
wiley   +1 more source

People Counting and Positioning Using Low‐Resolution Infrared Images for FeFET‐Based In‐Memory Computing

Advanced Electronic Materials, EarlyView.
In this work, low‐resolution infrared imaging is combined with a 28 nm FeFET IMC architecture to enable compact, energy‐efficient edge inference. MLC FeFET devices are experimentally characterized, and controlled multi‐level current accumulation is validated at crossbar array level.
Alptekin Vardar, Li Zhang, Alexander Rehmer, Marc Lupp, Subhashree Baskaran, Osama Abdelaal, Franz Müller, Nandakishor Yadav, Bing Li, Thomas Kämpfe   +9 more
wiley   +1 more source

Sport-related exertional heat illness hospitalisations in Victoria, Australia: Incidence and trend over 11 years

, 2019
Sport-related exertional heat illness hospitalisations in Victoria, Australia: Incidence and trend over 11 ...
L Fortington (13499989), S McMahon (11405180)   +1 more
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