Results 111 to 120 of about 11,123,934 (324)

Job Anxiety, Work-Related Psychological Illness and Workplace Performance [PDF]

This paper uses matched employee-employer data from the British Workplace Employment Relations Survey (WERS) 2004 to examine the determinants of employee job anxiety and work-related psychological illness.
Jones, Melanie K., Latreille, Paul L., Sloane, Peter J.   +2 more
core  

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

Advanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan, Soham Maity, Herbert Kavunja, Yuvarani Murali, Ting‐An Chen, Chang‐xin Huo, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +1 more source

Heat-related illness in individuals using psychiatric medication : 2016.

, 2016
Brochure; intended to be printed off on one sheet, front and back, and folded in thirds.; Harvested from the web on 6/2/16Common psychotropic medications that can impair the heat response -- Medical conditions and medications affect body temperature ...

core  

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Medicines can affect thermoregulation and accentuate the risk of dehydration and heat-related illness during hot weather

, 2015
What is Known and objectiveHot days are increasingly common and are often associated with increased morbidity and mortality, especially in the elderly.
Westaway, K., Frank, O., Rowett, D., Husband, A., McClure, A., Shute, R., Curtis, J., Edwards, S.   +7 more
core   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source

Addressing Heat-Related Illnesses in North Carolina [PDF]

In North Carolina and across the country, climate change has led to warmer average temperatures. Periods of extreme heat, an increasingly common weather event in North Carolina, can result in heat-related illness, including heat exhaustion, heat stroke ...
Rakowski, Meghan, Lawal, Khadeejatul-Kubraa, Siranosian, Elizabeth, Pavicevic, Katja   +3 more
core   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Neighborhood-Level Green Infrastructure and Heat-Related Health Risks in Tabriz, Iran: A Spatial Epidemiological Analysis

Atmosphere
Urban heat waves are intensifying under climate change, posing growing public health risks, particularly in rapidly urbanizing cities. Green infrastructure is widely promoted as a nature-based solution for heat mitigation, yet its health benefits may ...
Maryam Rezaei Ghaleh, Robert Balling
doaj   +1 more source

Warning signs and symptoms of heat-related illness [Spanish]

Warning signs and symptoms of heat-related illness [Spanish]Las enfermedades relacionadas con el calor se pueden prevenir. Aprenda los s\uedntomas y lo que tiene que hacer si usted o un ser querido muestran signos de una enfermedad relacionada con el ...

core