Results 91 to 100 of about 1,337,980 (309)

Heat release by controlled continuous-time Markov jump processes

open access: yes, 2012
We derive the equations governing the protocols minimizing the heat released by a continuous-time Markov jump process on a one-dimensional countable state space during a transition between assigned initial and final probability distributions in a finite ...
A. Alemany   +47 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Preparation of facilities for fundamental research with ultracold neutrons at PNPI [PDF]

open access: yes, 2009
The WWR-M reactor of PNPI offers a unique opportunity to prepare a source for ultracold neutrons (UCN) in an environment of high neutron flux (about 3*10^12 n/cm^2/s) at still acceptable radiation heat release (about 4*10^-3 W/g).
A.A. Zakharov   +36 more
core   +1 more source

Heat release methods

open access: yes, 2005
Heat release rate is one of the main inputs to zone and Computational Fluid Dynamics (CFD) fire models. It defines the fire size and its growth. This report presents the various methods found in the literature that have been used to predict the heat release rate.
Bounagui, A., Bénichou, N., Kashef, A.
openaire   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Review of thermal properties of graphite composite materials [PDF]

open access: yes
Flammability, thermal, and selected mechanical properties of composites fabricated with epoxy and other thermally stable resin matrices are described.
Kourtides, D. A.
core   +1 more source

Electron beam driven alkali metal atom source for loading a magneto-optical trap in a cryogenic environment

open access: yes, 2011
We present a versatile and compact electron beam driven source for alkali metal atoms, which can be implemented in cryostats. With a heat load of less than 10mW, the heat dissipation normalized to the atoms loaded into the magneto-optical Trap (MOT), is ...
Amsuess, R.   +8 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

A Comparison of Sensitivity Metrics for Two-Stage Ignition Behavior in Rapid Compression Machines [PDF]

open access: yes, 2017
A rapid compression machine (RCM) multi-zone model is used to simulate the ignition of primary reference fuel (PRF) mixtures that exhibit two-stage ignition behavior.
Allen, Casey, Wilson, David
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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