Results 81 to 90 of about 1,337,980 (309)
A thermodynamically reversible generalization of Diffusion Limited Aggregation
We introduce a lattice gas model of cluster growth via the diffusive aggregation of particles in a closed system obeying a local, deterministic, microscopically reversible dynamics.
D'Souza, Raissa M., Margolus, Norman H.
core +1 more source
Heat-Released Volatile Sulfur Compounds in Milk
Abstract Radioactive milk, obtained with the various chemical 35 S-labeled precursors: methionine, sodium sulfide, barium sulfide, and sodium sulfate, was heated to 90C for various periods and radioactivity of the volatiles determined. Radioactive hydrogen sulfide, mercaptans, organic sulfides, and derivatives of 2,4-dinitrophenyl-hydrazine were ...
R R, Pereira, W J, Harper, I A, Gould
openaire +2 more sources
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Determination of Bio-Oxidation Energy Released by Thermophiles in Secondary and Mixed Bio-Solids [PDF]
Reaction constants and heat release during thermophilic aerobic digestion of typical secondary and mixed sludges were determined. Maximum reaction constant, determined by measuring the amounts of biodegradable volatile suspended solids (bVSS) removed ...
Mohsen Nosrati +3 more
doaj
A Two-Zone Combustion Model for Knocking Prediction of Marine Natural Gas SI Engines
The further thermal efficiency improvement of marine natural gas engine is constrained by a knocking phenomenon that commonly occurs in gas-fueled spark-ignited engines. It plays an important role to investigate how the knocking occurs and how to predict
La Xiang, Enzhe Song, Yu Ding
doaj +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Effects of Surfactants on the Thermal and Fire Properties of Poly(Methyl Methacrylate)/Clay Nanocomposites [PDF]
Nanocomposites of poly(methyl methacrylate) (PMMA) with layered silicates and with polyhedral oligosilsesquioxanes (POSS) were prepared by bulk polymerization.
Jash, Panchatapa, Wilkie, Charles A.
core +2 more sources
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Comparative thermal performance test for GGBS and OPC concrete mixes [PDF]
The research investigates the effect of heating two concrete types and profiles to evaluate the most effective material during diurnal heating and cooling cycles.
Hart, A., Richardson, Alan, Walker, Sara
core

