Results 61 to 70 of about 1,337,980 (309)

A CFD Investigation of the Effects of Fuel Split Fraction on Advanced Low Temperature Combustion: Comparing a Primary Reference Fuel Blend and Ethanol

Frontiers in Mechanical Engineering, 2018
There is continuously growing interest in renewable biofuels for combustion engines to help reduce transportation energy consumption. In the present work, ethanol and a Primary Reference Fuel (PRF) were studied in an advanced LTC concept using CFD.
Mozhgan Rahimi Boldaji, Aimilios Sofianopoulos, Sotirios Mamalis, Benjamin Lawler   +3 more
doaj   +1 more source

Comparative Analysis of Heat Release, Bound Water Content and Compressive Strength of Alkali-Activated Slag-Fly Ash

Frontiers in Materials, 2022
Optimizing the mix composition of alkali-activated materials is sometimes overwhelming due to the higher number of potential parameters that could be varied compared to designing a mix based on Portland cement.
Shiju Joseph, Özlem Cizer
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

HEAT RELEASE IN NUCLEAR REACTORS [PDF]

, 1956
Discussions are included on energy sources and modes of local deposition of heat, fission fragment and BETA decay energy, neutron energy, energy release by BETA decay of activated nuclei, neutron flux distribution, gamma heating calculations, and integration of the gamma heating equation for simple cases. (M.H.R.)
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Energy and Exergy analysis of a light duty diesel engine operating at different altitudes

Revista Facultad de Ingeniería Universidad de Antioquia, 2009
La densidad del aire disminuye con el aumento de la altitud sobre el nivel del mar, este aspecto afecta el proceso de combustión, la formación de emisiones contaminantes y por tanto el desempeño del motor.
John Agudelo, Andrés Agudelo, Juan Pérez   +2 more
doaj  

Water vapor and the dynamics of climate changes [PDF]

, 2009
Water vapor is not only Earth's dominant greenhouse gas. Through the release of latent heat when it condenses, it also plays an active role in dynamic processes that shape the global circulation of the atmosphere and thus climate.
Adler, Allan, Allen, Arakawa, Bannon, Becker, Bengtsson, Bengtsson, Betts, Betts, Betts, Betts, Betts, Betts, Boer, Bordoni, Bosilovich, Brayshaw, Caballero, Caballero, Caballero, Caballero, Chang, Charney, Chen, Chou, Chou, Clement, Defant, Dickinson, Dima, Dima, Eady, Edmon, Emanuel, Emanuel, Emanuel, Emanuel, Emanuel, Fang, Folkins, Frierson, Frierson, Frierson, Frierson, Frierson, Geng, Graham, Gu, Gutowski, Held, Held, Held, Held, Held, Held, Held, Held, Herweijer, Hide, Hoffman, Hoskins, Hu, Iribarne, Jeffreys, Johanson, Juckes, Kiehl, Kim, Klinger, Knutson, Korty, Korty, Korty, Kushner, Kållberg, Lapeyre, Lee, Li, Lindzen, Lorenz, Lorenz, Lorenz, Lorenz, Lu, Neelin, Neelin, Neelin, Neelin, Neelin, O'Gorman, O'Gorman, O'Gorman, O'Gorman, O'Gorman, Orlanski, Otto-Bliesner, Paul A. O'Gorman, Peixoto, Pierrehumbert, Pierrehumbert, Previdi, Reed, Rind, Roads, Santer, Santer, Schneider, Schneider, Schneider, Schneider, Schneider, Schneider, Schneider, Schneider, Schneider, Schneider, Schneider, Seidel, Seidel, Seidel, Sherwood, Simmons, Simmons, Sobel, Stephens, Tanaka, Tapio Schneider, Thuburn, Trenberth, Trenberth, Trenberth, Trenberth, Trenberth, Trenberth, Uppala, Vecchi, Vecchi, Walker, Walker, Wentz, Wentz, Wernli, Willett, Xavier J. Levine, Yin, Zhang, Zurita-Gotor   +147 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source