Results 61 to 70 of about 844,270 (306)
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Planetary quarantine program Quarterly progress report, period ending Jun. 30, 1968 [PDF]
Dry heat sterilization experiments on bacillus spores, and lunar data system design for meeting planetary quarantine ...
core +1 more source
Fisher Zeroes and Singular Behaviour of the Two Dimensional Potts Model in the Thermodynamic Limit [PDF]
, 1997 The duality transformation is applied to the Fisher zeroes near the ferromagnetic critical point in the q>4 state two dimensional Potts model. A requirement that the locus of the duals of the zeroes be identical to the dual of the locus of zeroes in the ...
Abe R +22 more
core +2 more sources
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Lithium and potassium heat pipes for thermionic converters [PDF]
A prototypic heat pipe system for an out-of-core thermionic reactor was built and tested. The emitter of the concentric thermionic converter consists of the condenser of a tungsten heat pipe utilizing a lithium working fluid.
Kroeger, E. W., Miskolczy, G.
core +1 more source
Thermodynamics Characterization of Density models for an Effective Solar Water Heater Sizing [PDF]
, 2012 The problem faced in Sizing of an effective Solar Water Heater (SWH) by engineers to meet certain design requirement is highly enormous. Using the thermodynamic characterization relation and the knowledge of Solar Water Heater (SWH) density’s model ...
Aasa, S. A. +2 more
core
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Processing and Ductile-Brittle Transitions in PM Manganese Steels [PDF]
, 2005 YesBrittleness in manganese steels can be associated with processing in a "wet¿ [micro]climate resulting in the formation of continuous oxide networks.
Cias, A., Mitchell, Stephen C.
core
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source