Results 251 to 260 of about 352,389 (290)

Heat shock protein 70 and antibodies to heat shock protein 60 are associated with cerebrovascular atherosclerosis

Clinical Biochemistry, 2016
Heat shock proteins (Hsps) are produced by all cells, including vascular, to ensure stress protection. Damaged cells release Hsps in their local environment and systemic circulation. The aim of this study was to investigate the involvement and prognostic utility of serum Hsp60 and Hsp70, and the respective antibodies anti-Hsp60 and anti-Hsp70 in ...
Galović, Ružica, Flegar-Meštrić, Zlata, Vidjak, Vinko, Matokanović, Mirela, Barišić, Karmela   +4 more
openaire   +2 more sources

Autoantibodies against 60-kDa heat shock protein in schizophrenia

European Archives of Psychiatry and Clinical Neuroscience, 1998
Immunological abnormalities in schizophrenic patients have been reported for many years. However, the question of whether these parameters are involved in the pathophysiology of the disorder or represent treatment effects is still not answered. We investigated a combination of humoral and soluble immune parameters in 30 unmedicated schizophrenic ...
M J, Schwarz, M, Riedel, R, Gruber, N, Müller, M, Ackenheil   +4 more
openaire   +2 more sources

Legionella pneumophila has two 60-kilodalton heat-shock proteins

Current Microbiology, 1995
Legionella pneumophila is a thermotolerant bacterium. To learn more about the thermal adaptation of this organism, we studied the properties of the Legionella 60-kDa heat-shock protein (MopA, GroEL-analog, HtpB, Lp-Hsp60) in L. pneumophila and in an Escherichia coli strain containing the cloned gene.
M W, Lema, A, Brown
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Heat Shock Protein 60 in Skin Diseases

2019
In addition to serving as a stress regulatory/response protein, heat shock protein 60 (Hsp60) also plays important roles in disease mechanism and progression. This chapter summarizes all aspects of the current knowledge on Hsp60 related to various skin diseases, including acne, atopic dermatitis (AD), dermatitis herpetiformis (DH), vasculitis, Behcet’s
Papapit Tuchinda, Visith Thongboonkerd
openaire   +1 more source

Extracellular heat shock protein 60 (Hsp60) levels in children with septic shock

Inflammation Research, 2007
Recent data suggest that extracellular Hsp60 modulates the host innate immune response. We analyzed plasma Hsp60 levels in children admitted to a level III tertiary care PICU with septic shock.Blood samples were obtained from children meeting criteria for septic shock (n = 63), critically ill children without septic shock (n = 10), and healthy controls
D S, Wheeler, P, Lahni, K, Odoms, B R, Jacobs, J A, Carcillo, L A, Doughty, H R, Wong   +6 more
openaire   +2 more sources

Heat Shock Protein 60 Autoimmunity in Lyme Disease

2020
This chapter summarizes the discovery of a specific peptide sequence in heat shock protein (hsp) 60 as the molecular mimic of an immunodominant determinant in flagellin of Borrelia burgdorferi the etiological agent of Lyme disease (LD). The pathognomonic skin rash of LD, erythema migrans (EM), seen in about 50-70% of patients, usually begins as an ...
Zhizhong Dai, Stanley Stein, Stephanie Williams, Leonard H. Sigal   +3 more
openaire   +1 more source

Hepatic 60-kD heat-shock protein responses in alcoholic hepatitis

Hepatology, 1993
The precise mechanism of the pathogenesis of alcoholic hepatitis is unknown, but immune involvement may perpetuate and exacerbate the process. Heatshock proteins, normally protective, may be immunogenic and have been shown to induce antibody formation in some inflammatory conditions.
J, Koskinas, V R, Winrow, G L, Bird, J Y, Lau, B C, Portmann, D R, Blake, G J, Alexander, R, Williams   +7 more
openaire   +2 more sources

Optimization of Salmonella Enteritidis recombinant heat shock protein 60 production

Polish Journal of Veterinary Sciences, 2011
The aim of the study was to optimize conditions for producing Salmonella Enteritidis recombinant heat shock protein 60 (rHsp60). Seven Escherichia coli host strains (Rosetta, Turner, C41, C43, Origami, BL21pLys, Rosetta pLys) were transformed by a recombinant plasmid containing Hsp60 gene from Salmonella Enteritidis, and then cultured and induced by ...
K, Rainczak, J, Bajzert, J, Galli, A, Selera, A, Wieliczko, J, Borkowski, T, Stefaniak   +6 more
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Heat-shock Protein 60 and Cardiovascular Disease: A Paradoxical Role

Future Cardiology, 2008
Heat-shock proteins (HSPs) are members of a highly conserved group of proteins that are induced in response to stress and injury. These proteins have protective properties, and can protect the heart from injury. HSP60 is found in the mitochondria and cytosol, and has essential intracellular functions including folding key proteins after their import ...
Anne A, Knowlton, Uma, Srivatsa
openaire   +2 more sources

Molecular detection and characterisation of fungal heat shock protein 60

Mycoses, 2011
SummaryHeat shock proteins (Hsp) are highly conserved molecules, which are both constitutively expressed and up‐regulated in response to various stress conditions. In particular, fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties.
Reinhard B, Raggam, Helmut J F, Salzer, Egon, Marth, Bettina, Heiling, Astrid H, Paulitsch, Walter, Buzina   +5 more
openaire   +2 more sources