Results 251 to 260 of about 347,980 (289)

Heat-shock Protein 60 and Cardiovascular Disease: A Paradoxical Role

Future Cardiology, 2008
Heat-shock proteins (HSPs) are members of a highly conserved group of proteins that are induced in response to stress and injury. These proteins have protective properties, and can protect the heart from injury. HSP60 is found in the mitochondria and cytosol, and has essential intracellular functions including folding key proteins after their import ...
Anne A, Knowlton, Uma, Srivatsa
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Role of heat shock protein 60 (HSP60) on paraquat intoxication

Journal of Applied Toxicology, 2001
AbstractThe possibility of establishing a new method of treatment against pulmonary fibrosis caused by acute paraquat intoxication, which takes into consideration the role of heat shock protein 60 (HSP60), was investigated in paraquat‐exposed rat lung mitochondria.
A, Kaetsu, T, Fukushima, S, Inoue, H, Lim, M, Moriyama   +4 more
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Heat Shock Protein 60 in Skin Diseases

2019
In addition to serving as a stress regulatory/response protein, heat shock protein 60 (Hsp60) also plays important roles in disease mechanism and progression. This chapter summarizes all aspects of the current knowledge on Hsp60 related to various skin diseases, including acne, atopic dermatitis (AD), dermatitis herpetiformis (DH), vasculitis, Behcet’s
Papapit Tuchinda, Visith Thongboonkerd
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Molecular detection and characterisation of fungal heat shock protein 60

Mycoses, 2011
SummaryHeat shock proteins (Hsp) are highly conserved molecules, which are both constitutively expressed and up‐regulated in response to various stress conditions. In particular, fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties.
Reinhard B, Raggam, Helmut J F, Salzer, Egon, Marth, Bettina, Heiling, Astrid H, Paulitsch, Walter, Buzina   +5 more
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The expression of heat shock protein 60 in patients with dilated cardiomyophathy

Basic Research in Cardiology, 1999
Heat shock proteins (hsps) have been shown to be important antigens in a number of autoimmune diseases. We have previously shown the presence of autoantibodies against hsp60 in a high proportion of patients with dilated cardiomyopathy (DCM). This study set out to investigate the expression of hsp60 in the myocardium of 30 patients with DCM and a ...
N, Latif, P M, Taylor, M A, Khan, M H, Yacoub, M J, Dunn   +4 more
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Autoantibodies against 60-kDa heat shock protein in schizophrenia

European Archives of Psychiatry and Clinical Neuroscience, 1998
Immunological abnormalities in schizophrenic patients have been reported for many years. However, the question of whether these parameters are involved in the pathophysiology of the disorder or represent treatment effects is still not answered. We investigated a combination of humoral and soluble immune parameters in 30 unmedicated schizophrenic ...
M J, Schwarz, M, Riedel, R, Gruber, N, Müller, M, Ackenheil   +4 more
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[Studies of heat shock protein 60 and heat shock protein 70 in oral lichen planus].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2006
To study the role of heat shock protein (HSP) 60 and HSP70 in the pathogenesis of oral lichen planus (OLP).The immunohistochemical SP methods were used to detected the expression of HSP60 and HSP70 in 62 cases of oral lichen planus, 10 cases of normal oral mucosa, 21 cases of chronic discoid lupus erythematosus (DLE), 10 cases of benign lymphoadenosis ...
Ping, Di, Yan, Gao
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The 60 kDa Heat Shock Proteins in the Hyperthermophilic ArchaeonSulfolobus shibatae

Journal of Molecular Biology, 1995
One of the most abundant proteins in the hyperthermophilic archaeon Sulfolobus shibatae is the 59 kDa heat shock protein (TF55) that is believed to form a homo-oligomeric double ring complex structurally similar to the bacterial chaperonins. We discovered a second protein subunit in the S.
H K, Kagawa, J, Osipiuk, N, Maltsev, R, Overbeek, E, Quaite-Randall, A, Joachimiak, J D, Trent   +6 more
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Heat Shock Protein 60 Autoimmunity in Lyme Disease

2020
This chapter summarizes the discovery of a specific peptide sequence in heat shock protein (hsp) 60 as the molecular mimic of an immunodominant determinant in flagellin of Borrelia burgdorferi the etiological agent of Lyme disease (LD). The pathognomonic skin rash of LD, erythema migrans (EM), seen in about 50-70% of patients, usually begins as an ...
Zhizhong Dai, Stanley Stein, Stephanie Williams, Leonard H. Sigal   +3 more
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A nuclear protein associated with lethal heat shock of HL-60 cells

Experimental Cell Research, 1992
The responses to stress in living cells are well known. Thermal stress causes decreased protein synthesis as well as rapid induction of heat shock proteins (hsps), or alternately termed stress proteins (sps). The exposure of cultured promyelocytic leukemia cells (HL-60) to a 45 degrees C lethal heat shock for 1 h elicited synthesis and phosphorylation ...
J L, Pipkin, W G, Hinson, L E, Lyn-Cook, E R, Burns, D, Sheehan, D A, Casciano   +5 more
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