Results 251 to 260 of about 171,704 (286)

The expression of heat shock protein 60 in patients with dilated cardiomyophathy

Basic Research in Cardiology, 1999
Heat shock proteins (hsps) have been shown to be important antigens in a number of autoimmune diseases. We have previously shown the presence of autoantibodies against hsp60 in a high proportion of patients with dilated cardiomyopathy (DCM). This study set out to investigate the expression of hsp60 in the myocardium of 30 patients with DCM and a ...
N, Latif, P M, Taylor, M A, Khan, M H, Yacoub, M J, Dunn   +4 more
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Autoantibodies against 60-kDa heat shock protein in schizophrenia

European Archives of Psychiatry and Clinical Neuroscience, 1998
Immunological abnormalities in schizophrenic patients have been reported for many years. However, the question of whether these parameters are involved in the pathophysiology of the disorder or represent treatment effects is still not answered. We investigated a combination of humoral and soluble immune parameters in 30 unmedicated schizophrenic ...
M J, Schwarz, M, Riedel, R, Gruber, N, Müller, M, Ackenheil   +4 more
openaire   +2 more sources

The 60 kDa Heat Shock Proteins in the Hyperthermophilic ArchaeonSulfolobus shibatae

Journal of Molecular Biology, 1995
One of the most abundant proteins in the hyperthermophilic archaeon Sulfolobus shibatae is the 59 kDa heat shock protein (TF55) that is believed to form a homo-oligomeric double ring complex structurally similar to the bacterial chaperonins. We discovered a second protein subunit in the S.
H K, Kagawa, J, Osipiuk, N, Maltsev, R, Overbeek, E, Quaite-Randall, A, Joachimiak, J D, Trent   +6 more
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[Studies of heat shock protein 60 and heat shock protein 70 in oral lichen planus].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2006
To study the role of heat shock protein (HSP) 60 and HSP70 in the pathogenesis of oral lichen planus (OLP).The immunohistochemical SP methods were used to detected the expression of HSP60 and HSP70 in 62 cases of oral lichen planus, 10 cases of normal oral mucosa, 21 cases of chronic discoid lupus erythematosus (DLE), 10 cases of benign lymphoadenosis ...
Ping, Di, Yan, Gao
openaire   +1 more source

Heat Shock Protein 60 Autoimmunity in Lyme Disease

2020
This chapter summarizes the discovery of a specific peptide sequence in heat shock protein (hsp) 60 as the molecular mimic of an immunodominant determinant in flagellin of Borrelia burgdorferi the etiological agent of Lyme disease (LD). The pathognomonic skin rash of LD, erythema migrans (EM), seen in about 50-70% of patients, usually begins as an ...
Zhizhong Dai, Stanley Stein, Stephanie Williams, Leonard H. Sigal   +3 more
openaire   +1 more source

A nuclear protein associated with lethal heat shock of HL-60 cells

Experimental Cell Research, 1992
The responses to stress in living cells are well known. Thermal stress causes decreased protein synthesis as well as rapid induction of heat shock proteins (hsps), or alternately termed stress proteins (sps). The exposure of cultured promyelocytic leukemia cells (HL-60) to a 45 degrees C lethal heat shock for 1 h elicited synthesis and phosphorylation ...
J L, Pipkin, W G, Hinson, L E, Lyn-Cook, E R, Burns, D, Sheehan, D A, Casciano   +5 more
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Behçet's disease and antibody titers to various heat-shock protein 60s

Ocular Immunology and Inflammation, 1999
It has been suggested that the 65 kDa heat-shock protein (HSP) of Streptococcus in recurrent aphthae within the oral cavity may be involved in the uveoretinitis of Behçet's disease, possibly through sensitization of the immune system. To investigate this possibility, we examined serum antibody titers for various members of the 60 kDa family of HSPs and
T, Tanaka, N, Yamakawa, N, Koike, J, Suzuki, F, Mizuno, M, Usui   +5 more
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Expression of the 60 kDa heat shock protein in normal and inflamed liver

Journal of Hepatology, 1993
The 60 kDa heat shock proteins (HSP 60) have been well conserved throughout evolution and are highly immunogenic. Cross-reactivity between bacterial and mammalian HSP 60 is considered a likely mechanism in the pathogenesis of autoimmune diseases. T cell and B cell reactivity to HSP 60 is found in patients with rheumatoid or juvenile arthritis, and the ...
A W, Lohse, H P, Dienes, J, Herkel, E, Hermann, W, van Eden, K H, Meyer zum Büschenfelde   +5 more
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Heat Shock Protein 60 and Type I Diabetes

1999
Type I diabetes is characterised by the destruction of pancreatic insulin secreting beta cells and is commonly believed to have an autoimmune aetiology. During the clinically silent, early stages of disease the pancreas is infiltrated by inflammatory cells which mediate beta cell damage.
S. G. Newton, D. M. Altmann
openaire   +1 more source

Immunopositivity of heat shock protein 60 as a biomarker of bronchial carcinogenesis

The Lancet Oncology, 2005
CAPPELLO, Francesco, Di Stefano, A., D'Anna, S., Donner, C., ZUMMO, Giovanni   +4 more
openaire   +2 more sources