Results 81 to 90 of about 177,270 (246)

CHARACTERIZATION OF HEAT SHOCK PROTEINS IN BRUCELLA ABORTUS AND INTERACTION OF THESE PROTEINS WITH PATIENT AND CONTROL SERA

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2008
BACKGROUND AND OBJECTIVE: The bacteria begin to synthesize heat shock proteins (hsp) when facing elevated temperatures. Some of the hsps recognized during infection by host immune system.
R Rajabnia,, N Amirmozaffari,, F Ghazi,, A Mostafazadeh, A Mostafaie   +4 more
doaj  

Identification of proteins differentially expressed by glutamate treatment in cerebral cortex of neonatal rats

Laboratory Animal Research, 2019
Glutamate leads to neuronal cell damage by generating neurotoxicity during brain development. The objective of this study is to identify proteins that differently expressed by glutamate treatment in neonatal cerebral cortex. Sprague-Dawley rat pups (post-
Ju-Bin Kang, Dong-Ju Park, Phil-Ok Koh
doaj   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Heat stress induces both apoptosis and necrosis in normal human osteoblasts without heat shock protein-60 (HSP60) release [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2013
Thermal trauma can irreversibly damage bone cells; however, the mechanisms by which thermal trauma affects thebone microenvironment are poorly characterized.
Kanokwan Charoonpatrapong-Panyayong, Baramee Chanchayanon, Woraphong Panyayong   +2 more
doaj  

Evaluation of circulatory and salivary levels of heat shock protein 60 in periodontal health and disease

Indian Journal of Dental Research, 2014
Background: Self-antigens such as heat shock protein 60 (HSP 60) have recently been implicated in the periodontal disease pathogenesis. There is scant evidence regarding HSP 60 levels in circulation and saliva following periodontal disease and its ...
R Ramya Nethravathy, Swarna Alamelu, K V Arun, TSS Kumar   +3 more
doaj   +1 more source

Ti‐Doping Activates Adjacent Zr Sites in Bimetallic MOFs for Cooperative Phospholipid Removals in Human Biomonitoring

Advanced Science, EarlyView.
Ti‐doped Zr/Ti bimetallic MOFs activate neighboring Zr sites to selectively capture phospholipids from serum through cooperative interactions. In nontargeted screening, the material minimizes matrix interference, expands detectable feature coverage, and enables broad recovery of diverse chemical hazards, providing a powerful cleanup strategy for LC ...
Yanmin Liang, Hongyue Ma, Feier Bai, Jing Zhang, Yan Qi, Bing Shao   +5 more
wiley   +1 more source

Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations

Advanced Science, EarlyView.
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford, Matthew Tamasi, Elena Di Mare, Adam J. Gormley   +3 more
wiley   +1 more source

Strongyloides ratti : Identification, isolation and characterisation of Heat Shock Protein 10 and Heat Shock Protein 60

, 2009
S. stercoralis and S. ratti are intestinal parasitic nematodes infecting humans and rats. Both nematodes present extraordinary life cycles, comprising a free-living generation in addition to parasitic stages. To better understand the parasite?host relationship, the study of host defence?modulating molecules in parasitic systems may likely reveal new ...
Tazir, Yasmina, Justus Liebig University Giessen   +1 more
openaire   +2 more sources

Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform Toward Non‐Invasive Diagnostics

Advanced Science, EarlyView.
Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform toward Non‐Invasive Diagnostics is a nature‐inspired strategy that engineers controlled randomness within block copolymer lamellae to achieve optical isotropy without compromising nanoscale periodicity.
Jin Man Kim, Wonsik Kim, Wansun Kim, Yeon‐Hee Kim, Samjin Choi, Jang Hwan Kim, Hyeong Min Jin   +6 more
wiley   +1 more source

Engineering Synergistic Intra‐/Intermolecular Conformational Locking via Side‐Chain Branching: A β‐Sheet‐Inspired Strategy for Planar NIR‐II Phototheranostic Aggregates

Advanced Science, EarlyView.
A bio‐inspired side‐chain branching strategy is developed to orchestrate a dual noncovalent conformational locking (NoCL) network, enabling the construction of perfectly planar NIR‐II phototheranostic aggregates. Such structural precision maximizes light‐harvesting efficiency and optimizes exciton dynamics, ensuring synchronized enhancements in NIR‐II ...
Cheng Lu, Qian Jia, Bo Wu, Chao Li, Ryan T. K. Kwok, Tie‐Gen Chen, Jianwei Sun, Zheng Zhao, Teng‐Teng Chen, Zhongliang Wang, Jacky W. Y. Lam, Ben Zhong Tang   +11 more
wiley   +1 more source