Results 211 to 220 of about 306,716 (312)

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong   +5 more
wiley   +1 more source

Fabrication of Cu/SiC Surface Composite via Thermo-Mechanical Process (Friction Stir Processing) for Heat Sink Application. [PDF]

open access: yesMaterials (Basel)
Kumar H   +6 more
europepmc   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

open access: yesAnnals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian   +9 more
wiley   +1 more source

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro   +3 more
wiley   +1 more source

Contra‐Diffusion Engineering of Single‐Atom Catalytic Interlayers Enables Reversible Sulfur Redox Chemistry

open access: yesAngewandte Chemie International Edition, EarlyView.
A contra‐diffusion strategy is introduced to grow uniformly distributed Co–Nx single‐atom catalysts (CoSAs) within a carbonized aramid nanofiber (CANF) interlayer. The resulting CD‐CANF enables efficient polysulfide regulation, low metal loading, and exceptional long‐term cycling stability in lithium–sulfur batteries. ABSTRACT Achieving durable lithium–
Yan‐Jhang Chen   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy