Results 201 to 210 of about 1,604,851 (292)

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao   +12 more
wiley   +1 more source

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

open access: yesAdvanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi   +13 more
wiley   +1 more source

That heat sinking feeling

open access: yesMaterials Today, 2013
openaire   +1 more source

Gastrointestinal Heat Sink

open access: yesMedicine & Science in Sports & Exercise, 2018
Eric DB Goulet   +2 more
openaire   +2 more sources

Metaheuristic aided structural topology optimization method for heat sink design with low electromagnetic interference. [PDF]

open access: yesSci Rep
Al Ali M   +6 more
europepmc   +1 more source

Experimental Investigation and CFD Analysis of a Y-Fractal Microchannel Based Heat Sink [PDF]

open access: yes, 2015
Wu, Hongwei   +4 more
core  

Core and π‐Bridge Engineering to Deconstruct Y6‐Series into Modular Non‐Fused Acceptors: DFT‐Guided Structure‐Property Map for Organic Solar Cells

open access: yesAdvanced Electronic Materials, EarlyView.
The rigid fused backbone of Y6‐series acceptors is deconstructed into a modular, non‐fused A‐π‐A′‐π‐A architecture. Comprehensive quantum chemical simulations reveal that strategic core and π‐bridge engineering preserves strong near‐infrared light‐harvesting and enhances intramolecular charge‐transfer character.
Qurat ul Ain   +7 more
wiley   +1 more source

Controllable Superconductivity in Suspended NbSe2

open access: yesAdvanced Electronic Materials, EarlyView.
Suspended NbSe2${\rm NbSe}_2$ provides two complementary routes for controlling superconducting transport. Gate‐driven deformation strains the suspended crystal and tunes its critical temperature and current. Weak thermal anchoring enhances thermal feedback, contributing to multistep hysteresis and negative differential resistance.
Ruihuan Fang   +14 more
wiley   +1 more source

A Quantitative Lithium Inventory Framework for Anode‐Free Lithium Metal Batteries

open access: yesAdvanced Energy Materials, EarlyView.
A component‐resolved lithium inventory framework quantitatively tracks Li redistribution across the cell in anode‐free NMC622||Cu pouch cells throughout cycling. Three sequential degradation stages are identified: formation‐driven cathode Li depletion, midlife inactive Li0 accumulation, and late‐stage runaway SEI thickening. The cathode, as the sole Li
Wurigumula Bao   +9 more
wiley   +1 more source

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