Abstract Maintaining consistent quality in the manufacturing of biotherapeutic proteins in mammalian cell culture is challenging, with unplanned deviations causing inconsistencies and potential batch failure. Current methods for monitoring and controlling critical process parameters (CPPs) rely on slow, labor‐intensive offline analyses.
Matthew Banner +12 more
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Improved Thermo-Hydraulic Stability and Boiling Heat Transfer Through a Novel Three-Layer Microchannel Heat Sink with 3/4 Open-Ring Pin Fin Arrays. [PDF]
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A stereotactic laser interstitial thermal therapy strategy to flank dense calcifications within epileptogenic lesions: illustrative case. [PDF]
De La Peña NM +4 more
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Recent Developments in Novel TPMS Lattice Materials: Design Optimization, Performance Control, and Applications in Biomimetic Scaffolds. [PDF]
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Numerical simulation of heat transfer and fluid characteristics in micro-channels with obliquely arranged capsule-shaped ribs and optimization study of structural parameters. [PDF]
Yao J +8 more
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Dramatic increase in ecosystem respiration causes record-breaking atmospheric CO<sub>2</sub> growth rate in 2024. [PDF]
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Spatiotemporal patterns and driving mechanisms of terrestrial carbon sinks in Jiangxi Province, subtropical China. [PDF]
Song X, Chen X, Zheng B, Wan W.
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Characterization of Heat Sink Flow Bypass in Plate Fin Heat Sinks
Heat Transfer, Volume 5, 2002Experimental testing has been performed on two plate fin heat sinks in order to examine flow bypass phenomenon. The present study examines pressure drop and thermal resistance as well as flow velocities within the heat sinks. Tests are performed for bypass channel/fin height ratios of 0.25, 0.5, 0.75 and 1 with approach velocities from 2 to 8 m/s.
W. Leonard +3 more
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A method to rank heat sinks in practice: the heat sink performance tester
Semiconductor Thermal Measurement and Management IEEE Twenty First Annual IEEE Symposium, 2005., 2005One way of cooling electronic devices is through enlarging the surface that is in contact with a fluid (usually air) by attaching a heat sink. Since literally thousands of heat sinks are available many designers are confronted with the question: which one? Very often the designer's choice is based on cost and manufacturer's data.
C.J.M. Lasance, H.J. Eggink
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Conventional heat sinks for processors achieve improved heat transfer efficiency by impinging ambient air over stationary fins. Further improvement in the air film heat transfer coefficient through increased air speed becomes asymptotic and invariably results in undesirable acoustic noise.
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