Results 81 to 90 of about 5,306,758 (279)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Effects of dietary changes on heat stress in broiler and Kampung chickens [PDF]

open access: yes, 2012
Poultry meat production has increased drastically over the last 35 years. Most developing countries are in the tropics and often have high ambient temperatures.
Syafwan, W.
core  

Heat acclimation for protection from exertional heat stress [PDF]

open access: yes, 2016
This is the protocol for a review and there is no abstract. The objectives are as follows:\ud \ud To assess the effects of heat acclimation interventions aimed at protecting health and performance from exertional heat ...
Skein, Melissa   +14 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Flow patterns and heat transfer for flow boiling in small to micro diameter tubes [PDF]

open access: yes, 2008
An overview of the recent developments in the study of flow patterns and boiling heat transfer in small to micro diameter tubes is presented. The latest results of a long-term study of flow boiling of R134a in five vertical stainless steel tubes of ...
Karayiannis, TG   +3 more
core   +4 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Sun Safe Workspace #1: Overview of Florida’s Tailored Sun Safety Extension Program for Outdoor Professionals

open access: yesEDIS
To address the health needs of Floridians, Sun Safe Workspace was developed and offered by UF/IFAS Extension professionals. This tailored program aims to fill an identified gap in cancer prevention programming through classroom or community learning ...
Melissa J. Vilaro   +13 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Heat Stress among Dock Workers: Prevalence and Factors Associated with it Working in Port Area in South India: A Cross-Sectional Study

open access: yesJournal of Public Health and Primary Care
Background: Heat stress is a significant occupational health hazard worldwide, particularly in tropical regions where dock workers are exposed to high temperatures and humidity for extended periods.
Suneeta Ronanki   +2 more
doaj   +1 more source

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