Results 111 to 120 of about 2,047,625 (245)

Associations of compound hot extremes and heat waves with first-ever stroke morbidity in the context of climate change

Advances in Climate Change Research
Climate change has increased the frequency and intensity of abnormal weather, with current daytime and nighttime temperatures being higher than their historical counterparts. Previous studies have focused on exploring the health hazards of absolute heat (
Chen-Lu Yang, Ming-Wei Wang, Zhou-Peng Ren, Yi-Ke Li, Yong-Lin Hou, Cun-Rui Huang, Jun-Zhe Bao   +6 more
doaj   +1 more source

Strategy of Triple‐Gradient in Binary Pixels for Flexible Pressure Sensing with High Sensitivity and Wide‐Range Linearity

Advanced Science, EarlyView.
A flexible pressure sensor with triple‐gradient design of conductivity, modulus, and dimension in binary micro‐dome pixels is proposed. Based on precisely‐designed CNT/PDMS matrix, the device exhibits a linear sensitivity of 974.1 kPa−1 across range up to 1.8 MPa (R2 > 0.99), offering an effective strategy for potential applications in healthcare ...
Yifan Liu, Xiao Xu, Fengming Hu, Yuanzhe Liang, Zidong Yin, Biao Qi, Ruolin Liu, Ziyi Dai, Jianyi Luo, Bingpu Zhou   +9 more
wiley   +1 more source

A Rigid–Foldable Kirigami‐Inspired Metamorphic Mechanism With Programmable Motion Modes and Self‐Locking

Advanced Science, EarlyView.
Geometric constraint reconfiguration enables a rigid–foldable kirigami‐inspired mechanism to switch between twisting, directional translation, and self‐locking states. By encoding multifunctionality directly into its architecture, the mechanism achieves multimodal motion and passive locking without reassembly, providing a compact platform for adaptive ...
Jianlin Wang, Zhongmin Song, Ketao Zhang
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Geometry‐Encoded Actuation as a Structural Interaction Layer in Origami Robots

Advanced Science, EarlyView.
We present geometry‐encoded actuation (GEA), a design framework that integrates multistable origami with liquid crystal elastomer actuators to encode environmental interactions into autonomous structural responses. GEA enables programmable shape transformation without continuous sensing or complex control, achieving robust adaptive manipulation and ...
Jianshu Zhou, Yitong Li, Junda Huang, Ian Zhang, Haoran Liu, Boyuan Liang, Yiyuan Zhang, Xiaohui Xiao, Qiguang He   +8 more
wiley   +1 more source

Effect of built environment on the association between nighttime heat exposure and mortality in stroke patients: A case-crossover study in Shandong Province, China

Ecotoxicology and Environmental Safety
Background: Short-term exposure to extreme heat has been increasingly linked to cardiovascular mortality. However, limited evidence exists regarding the specific impact of nocturnal heat exposure on mortality among stroke patients, and the heterogeneity ...
Qiyong Cao, Ying Yu, Siyu Sun, Qiongqi Zhang, Chao Liu, Wanning Xia, Jing Wei, Chunxiang Shi, Bingyin Zhang, Zilong Lu, Xiaolei Guo, Xianjie Jia   +11 more
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

MRI and MR Spectroscopy Features of Heat Stroke: A Case Report

, 2018
Heat stroke is the outcome of over heat stress that results in multiorgan dysfunction with a tendency for central nervous system damage. Brain is very sensitive to hyperthermia, especially the cerebellum that has selective vulnerability to heat stroke ...
Umit Tuzun, YILMAZ, TEMEL FATİH, TOPRAK, HÜSEYİN, Serhat Guler, Tuzun, Umit, Alpay Alkan, Aralasmak, Ayse, ALKAN, ALPAY, Huseyin Toprak, Ayse Aralasmak, Guler, Serhat, Temel Fatih Yilmaz   +11 more
core   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source

Influence of the South Asian High and Western Pacific Subtropical High Pressure Systems on the Risk of Heat Stroke in Japan

Atmosphere
Weather patterns substantially influence extreme weathers in Japan. Extreme high temperature events can cause serious health problems, including heat stroke.
Takehiro Morioka, Kenta Tamura, Tomonori Sato   +2 more
doaj   +1 more source