Results 61 to 70 of about 1,925,814 (246)

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Nuclear factor erythroid 2-related factor 2 gene expression in patients with heat stroke and its association with oxidative stress and inflammation: a prospective study

Frontiers in Immunology
IntroductionHeat strokes represent a critical health issue with high mortality when severe, yet treatments are limited and do not target core pathogenic mechanisms.
Guodong Lin, Guodong Lin, Guodong Lin, Guodong Lin, Haiyang Guo, Bingling Yin, Chongxiao Xu, Ting Chen, Yueli Zhao, Qiang Wen, Yu Shao, Zhiguo Pan, Zhiguo Pan, Zhiguo Pan   +13 more
doaj   +1 more source

Optimizing Hydroxychloroquine Blood Levels and Long‐Term Hydroxychloroquine Intake Could Lower Atherosclerotic Cardiovascular Disease Risk and Prevent Polypharmacy in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is the cornerstone of systemic lupus erythematosus (SLE) management with benefits extending beyond SLE control, including protection against atherosclerotic cardiovascular disease (ASCVD). Although HCQ blood levels reflect recent exposure and long‐term intake reflects medication adherence, the impact of longitudinal ...
Shivani Garg, Murray Urowitz, Charlie Dentz, Niriti Adhikari, Fauzia Hollnagel, Nathalie Costedoat‐Chalumeau   +5 more
wiley   +1 more source

Calycosin-7-O-β-D-glucoside reduces myocardial injury in heat stroke rats

Journal of the Formosan Medical Association, 2019
Background/purpose: Calycosin-7-O-β-D-glucoside (CG), a calycosin derivative compound derived from Astragali Radix, has protective effect against ischemia/reperfusion injury as well as bacterial endotoxin-induced vascular cell injury.
Cheng-Chia Tsai, Hsing-Hsien Wu, Ching-Ping Chang, Cheng-Hsien Lin, Hsi-Hsing Yang   +4 more
doaj   +1 more source

Mechanical Thrombectomy in Acute Stroke Patients with Moderate to Severe Pre-Stroke Disability

, 2022
BACKGROUND AND PURPOSE: Studies on mechanical thrombectomy (MT) in acute ischemic stroke (AIS) patients with preexisting disability are limited. We aimed to compare the outcomes of MT versus best medical treatment (BMT) in these patients. METHODS: In the
Gattringer, T., Sykora, M., Strambo, D., Neumann, Christian, Strambo, Davide, Deutschmann, H., Gattringer, Thomas, Mikšová, D., Krebs, Stefan, Lang, Wilfried, Ferrari, J., Deutschmann, Hannes, Posekany, Alexandra, Michel, Patrik, Posekany, A., Ferrari, Julia, Mikšová, Dominika, Hermann, Konstantin, Neumann, C., Sykora, Marek, Lang, W., Krebs, S., Gizewski, Elke, Hermann, K., Gizewski, E., Michel, P.   +25 more
core   +1 more source

Pathophysiologic and Therapeutic Perspectives Based on Thrombus Histology in Stroke [PDF]

, 2020
Recent advances in endovascular thrombectomy have enabled the histopathologic analysis of fresh thrombi in patients with acute stroke. Histologic analysis has shown that the thrombus composition is very heterogeneous between patients.
김병문, 김동준, 김영대, 남효석, 허지회   +4 more
core   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Severe heat stroke complicated by multiple cerebral infarctions: a case report

Journal of Medical Case Reports, 2021
Background Heat-related illnesses include symptoms such as heat syncope/cramps, heat exhaustion, and life-threatening heat stroke. Usually, a heat stroke causes cerebellar ataxia, cognitive impairment, dysphagia, and aphasia.
Ryo Kamidani, Hideshi Okada, Yuichiro Kitagawa, Keigo Kusuzawa, Masahiro Ichihashi, Yoshinori Kakino, Hideaki Oiwa, Ryu Yasuda, Tetsuya Fukuta, Naomasa Yoshiyama, Takahito Miyake, Haruka Okamoto, Kodai Suzuki, Noriaki Yamada, Tomoaki Doi, Takahiro Yoshida, Hiroaki Ushikoshi, Keisuke Kumada, Shozo Yoshida, Shinji Ogura   +19 more
doaj   +1 more source

Stroke Clinician Interviews the Co-Founders of Phagenesis

Stroke Clinician recently had the opportunity to interview Drs. Shaheen Hamdy, Chief Scientific Officer and Conor Mulrooney, Chief Operating Officer of Phagenesis. Drs.
Clinician, Stroke
core   +1 more source