Results 91 to 100 of about 12,345,819 (252)

Objective function for municipal heat supply systems’ structural optimization [PDF]

open access: yes, 2015
Modern heat supply systems in urban areas have the potential to heat supply cost reduction when using various alternative thermal energy sources. Availability of possible alternatives allows to select the source that generates a cheaper heat.
Sergiy V. Babich, Valentyn O. Davydov
core   +1 more source

Principles of process modeling of the heat supply systems operation

open access: yes, 2018
The problem of process modeling of heat supply systems operation with the appropriate of the special software is presented in the article. The purpose of the simulation is to identify the most likely and dangerous accidents, the quantitative and ...
Anna Doroshenko, Anastasiya Yusupova
core   +2 more sources

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Integration of heat pumps with heat extraction from the soil and air into building heating systems.

open access: yesTrudy Odesskogo Politehničeskogo Universiteta
The paper reviews the current state of heat supply systems for residential and public buildings. The need to use alternative energy sources for heat supply in residential and public buildings is shown.
Юрій Сергійович Рєпін   +1 more
doaj   +5 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Numerical Analysis of Heat Transfer in a Double-Pipe Heat Exchanger for an LPG Fuel Supply System

open access: yes
LPG fuel supply systems are increasingly important for improving energy efficiency and reducing carbon emissions in the shipping industry. The primary objective of this research is to investigate the heat transfer phenomena to enhance the thermal ...
Younghun Kim   +3 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Effect Of Operational Parameters On Heat and Mass Transfer In Generator of R134a/DMF Absorption Refrigeration System [PDF]

open access: yes, 2012
Vapour absorption refrigeration systems (VARS) has regained the attention due to their potential for renewable/waste heat utilization. To improve the efficiency of these systems, it becomes obligatory to make component level studies on processes. In this
Pasupathy, Balamurugan, Annamalai, Mani
core  

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