Results 91 to 100 of about 6,644,033 (400)
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Heat transfer in a recirculation zone at steady-state and oscillating conditions - the back facing step test case [PDF]
, 2008 Steady state and transient heat transfer is a very important aspect of any combustion process. To properly simulate gas to wall heat transfer in a turbulent flow, an accurate prediction of the flow and the thermal boundary layer is required.
Kok, J.B.W. +3 more
core +1 more source
International Journal of Energy Research, 2018 Thermal energy storage (TES) is a technology that stocks thermal energy by heating or cooling a storage medium so that the stored energy can be used later for heating and cooling applications and for power generation.
I. Sȃrbu, Alexandru Dorca
semanticscholar +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Cycling Joule Thomson refrigerator [PDF]
, 1983 A symmetrical adsorption pump/compressor system having a pair of mirror image legs and a Joule Thomson expander, or valve, interposed between the legs thereof for providing a, efficient refrigeration cycle is described.
Tward, E.
core +1 more source
Molecular Oncology, EarlyView.Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan +4 more
wiley +1 more source
Selective tube roughening increases heat transfer capability [PDF]
, 1966 Selectively roughening inside surfaces of tubes increases the heat transfer capabilities, but minimizes the pressure drop.
Carlson, L. W.
core +1 more source
, 2011 We demonstrate the possibility of achieving enhanced frequency-selective near-field radiative heat transfer between patterned (photonic crystal) slabs at designable frequencies and separations, exploiting a general numerical approach for computing heat ...
Alejandro W. Rodriguez +8 more
core +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source