Results 91 to 100 of about 4,498,847 (302)

Boiling and condensation in a liquid-filled enclosure [PDF]

, 1971
A combined experimental and analytical investigation of boiling and condensation in a liquid-filled enclosure, with water and Freon- 113 as the working fluids, is described.
Bergles A. E., Bar-Cohen Avram
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Condensation Heat Transfer Characteristics of Moist Air Outside Hydrophilic and Super-hydrophobic 3D Pin Fin Tube

Chemical Engineering Transactions, 2019
Three dimensional pin fin tube is an effective heat transfer element. It has been widely used in industry process. However, condensation heat transfer characteristic of moist air outside it has not been experimentally studied.
Yuheng Gu, Yudong Ding, Qiang Liao, Qian Fu, Xun Zhu, Hong Wang   +5 more
doaj   +1 more source

Mechanism of nucleate pool boiling heat transfer to sodium and the criterion for stable boiling [PDF]

, 1967
A comparison between liquid metals and other common fluids, like water, is made as regards to the various stages of nucleate pool boiling. It is suggested that for liquid metals the stage of building the thermal layer plays the most significant part in ...
Shai, Isaac
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Experimental study on flow boiling of ethylene glycol-water solution in sandblasted and microporous-structured copper narrow gap channels

Case Studies in Thermal Engineering
Narrow gap channel boiling heat transfer is considered one of the most promising cooling technologies for addressing high heat flux dissipation problems.
Qiushi Gu, Chen Zhao, Fangjun Hong, Chaoyang Zhang   +3 more
doaj   +1 more source

Conjugate Heat Transfer Characteristics in a Highly Thermally Loaded Film Cooling Configuration with TBC in Syngas

Aerospace, 2019
Future power equipment tends to take hydrogen or middle/low heat-value syngas as fuel for low emission. The heat transfer of a film-cooled turbine blade shall be influenced more by radiation.
Jing Ren, Xueying Li, Hongde Jiang
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Characteristic Analysis of Boiling Heat Transfer of R32 Refrigerant and Modeling Study of Heat Exchanger

Energies
This study experimentally investigates the boiling heat transfer characteristics of R32 and R410A refrigerants in heat exchangers, systematically analyzing the effects of tube thickness, saturation temperature, latent heat, liquid-phase density, and ...
Bo Yu, Chenjie Zhou, Wenxiao Chu, Yuye Luo   +3 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source