Results 81 to 90 of about 4,498,847 (302)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

MHD Flow of a Viscous Fluid over an Exponentially Stretching Sheet in a Porous Medium

open access: yesJournal of Applied Mathematics, 2014
Radiation effects on magnetohydrodynamic (MHD) boundary-layer flow and heat transfer characteristic through a porous medium due to an exponentially stretching sheet have been studied.
Iftikhar Ahmad   +7 more
doaj   +1 more source

Cooling of high-power-density computer components [PDF]

open access: yes, 1968
This report summarizes work carried out during the first two years of a research program sponsored by IBM Corporation. This study has elucidated a number of the heat-transfer characteristics of several fluorochemicals which have potential application as ...
Bakhru, N.   +2 more
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Modification on prediction method of heat transfer coefficient from a vertical-finite-length cylinder in saturated film boiling to discuss local heat transfer performance near the lower corner

open access: yesJournal of Thermal Science and Technology, 2018
Saturated film boiling heat transfer around a vertical-finite-length cylinder has been investigated analytically to predict the local heat transfer coefficients at the bottom and lower vertical surfaces.
Win PA PA MYO   +2 more
doaj   +1 more source

Parallel Triangular Channel System for Latent Heat Thermal Energy Storages

open access: yes, 2018
A computational investigation on thermal energy storage system using Phase Change Material (PCM) is accomplished. The system is a honeycomb structure made of parallel triangular channels and half of them are filled with PCM and the others are passed ...
A. ANDREOZZI   +7 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Influence of the heat transfer coefficient on heat transfer in a vibrating cylindrical cavity

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки
Heat transfer in a vibrating cylindrical air-filled cavity, where the heat flux on the walls is defined by the Newton–Richmann law, was studied numerically.
A. A. Gubaidullin, A. V. Pyatkova
doaj   +1 more source

Forced-convection condensation inside tubes [PDF]

open access: yes, 1971
High vapor velocity condensation inside a tube was studied analytically. The von Karman universal velocity distribution was applied to the condensate flow, pressure drops were calculated using the Lockhart- Martinelli method, and heat transfer ...
Baron, Anton G.   +2 more
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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