Results 61 to 70 of about 652,960 (307)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The Influence of Inclination Angle and Cooling Water Temperature on the Heat Transfer Performance of a Novel Closed Gravity Heat Pipe Exchanger

Zhileng xuebao, 2017
The heat transfer performance of a heat pipe using acetone as working fluid is experimentally studied and discussed in this paper. A novel heat pipe array was designed and expected to be utilized in integrated waste heat recovery equipment with higher ...
Li Penghui, Han Xiaoxing, Wang Yaxiong, Wu Wei   +3 more
doaj  

Visualization Experiment Study on Heat Transfer Characteristic and Limit of High-temperature Oscillating Heat Pipe

Yuanzineng kexue jishu
The high-temperature oscillating heat pipe (HTOHP) has broad application prospects in the field of high heat flux dissipation in high-temperature environments such as nuclear energy and aerospace because of its efficient heat transfer capability and ...
YANG Xin, JI Yulong
doaj   +1 more source

Heat transfer characteristics of thermo-syphon: Case study of modifying inclination angle of evaporator and condenser sections [PDF]

Research & Knowledge, 2015
Experiments were carried out to study the heat transfer characteristics of a thermosyphon when modifying the evaporator and condenser sections to be oriented at 0, 60 and 90 degrees with respect to the 70 degree inclination of the adiabatic section (Z ...
Kittipon Khangam, Narong Srihajong
doaj   +1 more source

Spreading and heat transfer characteristics of droplet on a heated substrate

Acta Physica Sinica, 2016
The spreading characteristics of a droplet on a heated substrate have direct influences on its spreading area and heat transfer, so the exploration in this aspect is of important significance for cooling electronic and aerospace equipments. In the present paper, the evolution model of a droplet on a heated solid substrate is established based on the ...
null Ye Xue-Min, null Li Yong-Kang, null Li Chun-Xi   +2 more
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Novel Multidimensional Characteristic Modeling of Incompressible Convective Heat Transfer

Journal of Applied Fluid Mechanics, 2016
A characteristic-based approach is developed for thermo-flow with finite volume methodology (FVM) in which multidimensional characteristic (MC) scheme is applied for convective fluxes.
S. E. Razavi, Tohid Adibi
doaj  

Наближена оцінка температурного стану керамічного ядерного палива в циліндричних твелах та впливу на нього процесів і параметрів конструкцій активної зони реактора [PDF]

, 2008
The approximate mathematical model of the temperature state of ceramic nuclear fuels in cylindrical fuel elements was proposed in the form of linear ordinary differential equation and the boundary conditions. The theory of heat conduction and assumptions
Chibisov, Dmytro, Romashov, Yury
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Two-phase Boiling Heat and Mass Transfer Characteristic within PWR CRUD Deposition

Yuanzineng kexue jishu, 2022
The porous chalk river unidentified deposit (CRUD) depositions not only increase the thermal resistance and lead to the deterioration of heat transfer, but also change the power distribution as a result of boron hideout. Therefore, accurate prediction of
LIU Yan;LIU Xiaojing;HE Hui
doaj