Results 41 to 50 of about 122,906 (266)

Experimental study on thermal-hydraulic performance of helically coiled tubes steam generator of lead-bismuth reactor

International Journal of Advanced Nuclear Reactor Design and Technology
The advantages of the helically coiled tube steam generator lie not only in its high heat transfer efficiency but also in its compact structure, which is initially used in Pb–Bi–SCO2 reactors, and its main function is to transfer the heat from the lead ...
Dandan Gu, Lina Zhu, Changzhi Xiao, Hongyi Yang   +3 more
doaj   +1 more source

Heat Transfer Characteristic Study on Downhole Cooling System of Drilling Instrument

Shiyou jixie, 2022
Improving the high-temperature resistant capacity of drilling instrument is an important research direction in petroleum engineering technology, and adding a cooling device in the drilling instrument is one of the solutions of downhole cooling system ...
Liu Ke, Gao Wenkai, Dou Xiurong, Wang Jiajin, Teng Xinmiao   +4 more
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Spreading and heat transfer characteristics of droplet on a heated substrate

Acta Physica Sinica, 2016
The spreading characteristics of a droplet on a heated substrate have direct influences on its spreading area and heat transfer, so the exploration in this aspect is of important significance for cooling electronic and aerospace equipments. In the present paper, the evolution model of a droplet on a heated solid substrate is established based on the ...
null Ye Xue-Min, null Li Yong-Kang, null Li Chun-Xi   +2 more
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Heat Transfer Capacity of Lotus-type Porous Copper Heat Sink for Air Cooling

Journal of Thermal Science and Technology, 2010
Lotus-type porous metal with many straight pores is attractive as a heat sink because larger heat transfer capacity is obtained due to the small diameter of the pores.
Hiroshi CHIBA, Tetsuro OGUSHI, Hideo NAKAJIMA   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Influence of Inclination Angle and Cooling Water Temperature on the Heat Transfer Performance of a Novel Closed Gravity Heat Pipe Exchanger

Zhileng xuebao, 2017
The heat transfer performance of a heat pipe using acetone as working fluid is experimentally studied and discussed in this paper. A novel heat pipe array was designed and expected to be utilized in integrated waste heat recovery equipment with higher ...
Li Penghui, Han Xiaoxing, Wang Yaxiong, Wu Wei   +3 more
doaj